Protein Alignment ZnT33D and Slc30a5

DIOPT Version :8

• Sequence 1: NP_723732.2
• Gene: ZnT33D / 326167
• FlyBaseID: FBgn0051860
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_075023.2
• Gene: Slc30a5 / 69048
• MGIID: 1916298
• Length: 761
• Species: Mus musculus
• Alignment Length: 490
• Identity: 103/491 (21%)
• Similarity: 204/491 (42%)
• Gaps: 113/491 (23%)

  Fly   191 WKRPTPVVLKSNQNYSANKNSENALDAKPQTATNTEETHGCINILKVPF--QSNLYYVPEKPSRQ 253
            |..|....|::....:..:::|:.|.             |.:.:..|.|  .:|:...|.|  |.
Mouse   318 WTHPITDQLRAMNRAAHQESTEHVLS-------------GGVVVSAVFFILSANILSSPSK--RG 367

  Fly   254 DKGS--GTSDFQPGAPE-TPIVENSAVDSDRKAVEIMPENVKNSEEKKIDNSDSTKTVTITGHSH 315
            .||:  |.|      || ||:..... |:.:.:.:.:|..:|:|.::.::.|||
Mouse   368 QKGTLIGYS------PEGTPLYHFMG-DAFQHSSQSVPRFIKDSLKQVLEESDS----------- 414

  Fly   316 ITAKWDGHCHFKERETGVDKAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLAS 380
                                  |::....| |..:|..:|:..|:|:|||.:.:|..|:|.|.::
Mouse   415 ----------------------RQIFYFLC-LNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSA 456

  Fly   381 FLISISALHLAGRPSSERLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIM 445
            .::.:.|..::...::...:||:.|.|::...::..|:.|:...:...::.|.::.. |||..::
Mouse   457 LVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPP-ELDTNML 520

  Fly   446 LITSALAILFNVIMAMQLQHGHSHSLPGVHKMSK-----DAGSVLGSKMILLLGKSVSMQYAAKG 505
            ...|...::.|:|......|.|||.    |..|:     |.|.                .:.|.|
Mouse   521 TPVSVGGLIVNLIGICAFSHAHSHG----HGASQGNCHSDHGH----------------SHHAHG 565

  Fly   506 H--------------ENINVRAAIIHVVGDIIQSFGVFVAALIIFFWPEWAFMDSVCTFVFSVLV 556
            |              .|.|:|...:||:.|.:.|.||.|:.::|..: .|...|.:|:...:||:
Mouse   566 HGHDHGHSHGFTGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQF-GWFIADPLCSLFIAVLI 629

  Fly   557 LVVTFKILRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNL------RIWALSINKVALSAH 615
            .:....:::|...||:...|.  |:|  |:..:::..::.:..|      ..|..|.:.||.:.|
Mouse   630 FLSVIPLIKDACQVLLLRLPP--DHE--KELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIH 690

  Fly   616 LAISKDADPQLILEEATTLIHKRFKFFETTIQIEE 650
            :.::.:...|.|:::.|.:: |.......|||:|:
Mouse   691 IQVTSEVLEQRIVQQVTGIL-KDAGVNNLTIQVEK 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT33D	NP_723732.2	CDF	350..651	CDD:273544	73/327 (22%)
		Cation_efflux	350..572	CDD:279834	55/241 (23%)
Slc30a5	NP_075023.2	CDF	426..725	CDD:273544	73/327 (22%)
		Cation_efflux	426..645	CDD:279834	55/241 (23%)
		His-rich loop	540..574		11/54 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900