Protein Alignment CG31689 and Abcg4

DIOPT Version :10

• Sequence 1: NP_001259954.1
• Gene: CG31689 / 326154
• FlyBaseID: FBgn0031449
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 615
• Identity: 220/615 - (35%)
• Similarity: 350/615 - (56%)
• Gaps: 38/615 - (6%)

  Fly    20 SPFNIIFEDLYYRVEVG---KDREKKSVLKGIKGTFKSGELTAIMGPSGAGKSSLMNILTGLTKS 81
            |..:|.|.:|.|.|..|   :.|..|::||.:.|.|...||..||||||||||:.||||.|..:|
Mouse    57 SAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRES 121

  Fly    82 GVSGKI-------EIGKARKLCGYIMQDDHFFPYFTVEETMLMAATLKISNQCVSLKEKRTLIDY 139
            |:.|:|       |:...||:..||||||...|:.||.|.|:::|.||:|.:   .:.|:.|:..
Mouse   122 GMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK---QEVKKELVTE 183

  Fly   140 LLNSLKLTKTRQTKCSNLSGGQKKRLSIALELIDNPAVLFLDEPTTGLDSSSSFDTIQLLRGLAN 204
            :|.:|.|.....|:.:.|||||:|||:|||||::||.|:|.||||:||||:|.|..:.|::.||:
Mouse   184 ILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAH 248

  Fly   205 EGRTIVCTIHQPSTNIYNLFNLVYVLSAGRCTYQGTPQNTVMFLSSVGLECPPYHNPADFLLECA 269
            .|||::|||||||..::.:|:.:|:||.|:|.::|...|.:.:|..:||.||.|||||||::|.|
Mouse   249 GGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVA 313

  Fly   270 NGDYGDQTEALAEAAKDIRWRYDQQLMQGEDADAPSETQVAKFNESQSPGQVQVQVQKIEIQNME 334
            :|:|||....|..|.:      :......|...:|.:.::.....:..|          |:..:|
Mouse   314 SGEYGDLNPMLFRAVQ------NGLCTMAEKKSSPGKNELPAHCPTCPP----------ELDPIE 362

  Fly   335 SSKDLTKHTYPPTEYMRLWLLIGRCHLQFFRDWTLTYLKLGIHVLCSILIGLFFGDSGSNATKQI 399
            |      ||:..:...:..:|..|..|...||..||:|:...|||..:||||.:...|.:|:|..
Mouse   363 S------HTFATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVF 421

  Fly   400 SNVGMIMIHCVYLWYTTIMPGILRYPAEIEIIRKETFNNWYKLRTYYLATIITSTPVHIIFSTVY 464
            :|.|.:....::|.:..:||.:|.:|.|:.:..:|..|.||.|:.||||..:...|..::...||
Mouse   422 NNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCPVVY 486

  Fly   465 ITIGYLMTDQPVEMDRFVKYLLSAVVVTICADGLGVFLGTVLNPVN-GTFVGAVSTSCMLMFSGF 528
            .:|.|.||.||.|..||:.:...|:...:.|..||:.:|.....:. .||||.|:...:|:||||
Mouse   487 CSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGF 551

  Fly   529 LILLNHIPAAMRFMAYISPLRYALENMVISLYGNQRGQLICPPTEFYCHFKNAVTVLRQFGMEDG 593
            .:....||..:::.:|:|.:||..|.:::::||.:||.|.|  .:..|.|::...:||:..:|:.
Mouse   552 FVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTC--LDEQCPFRDPQIILRELDVEEA 614

  Fly   594 DFGHNILMILIQIAIFKVLSYFTLKHKIKT 623
            ....:.|::.|.....::|:|..|::::|:
Mouse   615 KLYMDFLVLGIFFLALRLLAYLVLRYRVKS 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31689	NP_001259954.1	3a01204	15..622	CDD:273361	219/612 (36%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	220/615 (36%)