Protein Alignment TH1 and Nelfcd

DIOPT Version :10

• Sequence 1: NP_573123.1
• Gene: TH1 / 32607
• FlyBaseID: FBgn0010416
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_065605.3
• Gene: Nelfcd / 57314
• MGIID: 1926424
• Length: 582
• Species: Mus musculus
• Alignment Length: 576
• Identity: 316/576 - (54%)
• Similarity: 438/576 - (76%)
• Gaps: 9/576 - (1%)

  Fly     8 SGWQGRAKGQTNPEETL---EDNPQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQSGGSPEEVIS 69
            |.|...|.|..:.|:..   ||:.: ..||||.||.|.||||||.||..||||||:|||||.||.
Mouse    10 SEWGEEADGGQHQEDDSGEGEDDAE-VQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQ 73

  Fly    70 MLSENYKAVAQMANLLAEWLILAGVKVTEVQAMVENHLKEMILKSFDPKKADTIFTEEGETPDWL 134
            :|||||.||||..||||||||..||:..:||..||||||.:::|.|||:|||:|||||||||.||
Mouse    74 LLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWL 138

  Fly   135 TEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSISTAAQQIEVFSRVLKTSIVK 199
            .:||.|.|||.|.|:|||.:|||||||||:|||||||:|.||||:|||.||:|||||||:||:..
Mouse   139 EQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLAT 203

  Fly   200 FLN-NPDDVHGAIQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFNMKRLSQEIIKYALQNNQNV 263
            .|: ..:::...:.|.|:|||||:|||:::|.::.||:||::||..::|::||:.::|.:...:.
Mouse   204 ILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRVAQEVQRFAQEKGHDA 268

  Fly   264 TPITMALNGSAVYPQACQALTSMLTRNTLNPADITVLFRNYSGSDPPPIDLIRNPQFLELLVDAL 328
            :.||:||..:|.||:|||||.:||:|..||||||||||:.::..||||::|||.|.||:|.:.:|
Mouse   269 SQITLALGTAASYPRACQALGAMLSRGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSL 333

  Fly   329 FRSGVKINPEHKPKYMFLLAYASAVIDQPAKKRPMTERMLNKEELKSTIQAIEKAHTI-CNVDQG 392
            |:.|.|||.:||.||:.:||||::|::...|.:.::   :.|:|||||.:|||..|.: ||.::|
Mouse   334 FKPGAKINQDHKHKYIHILAYAASVVETWKKNKRVS---IGKDELKSTSKAIETVHNLCCNENKG 395

  Fly   393 STELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSYFKLSTDSCPTHLAVLDEVAAVHPTLQQQ 457
            ::||:|||.|||.||::|||.:||::|::..|.||.||:|.||..|.|||:|||::..|..|..|
Mouse   396 ASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQ 460

  Fly   458 ILFLLIRLFESKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYIKQCCAIEDTDISLIRYF 522
            :|.||::|||::..:|:::.|||:||.:|||||:||:||.|:||:.||::|....||||||||||
Mouse   461 VLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYF 525

  Fly   523 VTEVLETITHPYSPEFVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHYTTV 578
            |||||:.|..||:.:|||||||::||:.|.||::.||::|||:|||.|||:::..|
Mouse   526 VTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNFIVV 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TH1	NP_573123.1	TH1	2..576	CDD:398497	315/572 (55%)
Nelfcd	NP_065605.3	TH1	2..579	CDD:398497	315/572 (55%)