Protein Alignment TH1 and nelfcd

DIOPT Version :10

• Sequence 1: NP_573123.1
• Gene: TH1 / 32607
• FlyBaseID: FBgn0010416
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_957484.1
• Gene: nelfcd / 394165
• ZFINID: ZDB-GENE-040426-720
• Length: 579
• Species: Danio rerio
• Alignment Length: 583
• Identity: 313/583 - (53%)
• Similarity: 436/583 - (74%)
• Gaps: 19/583 - (3%)

  Fly     2 EVEYDDSG-WQGRAKGQTNPEETLEDN------PQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQ 59
            |..|..:| |:.:       :.::||.      ..|..::||:||.:.||||||.:|..||.|||
Zfish     3 EEYYSHAGEWEAQ-------DGSMEDGYGDAEADGKVQEDCLQKFSSRDYIMEPTVFNTLKSYFQ 60

  Fly    60 SGGSPEEVISMLSENYKAVAQMANLLAEWLILAGVKVTEVQAMVENHLKEMILKSFDPKKADTIF 124
            :|||||.||.:|||||.||||..||||||||..||:..:||..||||||.:::|.|||:|||:||
Zfish    61 AGGSPEHVIQLLSENYSAVAQTVNLLAEWLIQMGVEPAQVQERVENHLKSLLIKHFDPQKADSIF 125

  Fly   125 TEEGETPDWLTEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSISTAAQQIEVF 189
            |.|||||.||.:||.|.|||.|.|:|||.:|||||||||:|||||||:|.||||:|||.||:|||
Zfish   126 TVEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVF 190

  Fly   190 SRVLKTSIVKFLNNPD-DVHGAIQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFNMKRLSQEII 253
            ||||:||:...|:..: ::...:.|.|:|||||:|||:::|.::.:|:||::||..|:|:.||:.
Zfish   191 SRVLRTSLATLLDGGEQNLEKNLPEFAKMVCHGEHTYLFAQAMMSILAQEEQGGSAMRRIGQEVQ 255

  Fly   254 KYALQNNQNVTPITMALNGSAVYPQACQALTSMLTRNTLNPADITVLFRNYSGSDPPPIDLIRNP 318
            |||.:...:.:.||:||..:|.||:|||||.:||::..||||||||||:.:|..||||::|||.|
Zfish   256 KYAHERGHDASQITLALGTAAAYPRACQALGAMLSKGALNPADITVLFKMFSSMDPPPVELIRVP 320

  Fly   319 QFLELLVDALFRSGVKINPEHKPKYMFLLAYASAVIDQPAKKRPMTERMLNKEELKSTIQAIEKA 383
            .||:|.:.:||:.|.|||.:||.||:.:||||::|::...|.:.:.   :||:|||||.:|||..
Zfish   321 AFLDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVETWKKNKRVN---INKDELKSTSKAIETV 382

  Fly   384 HTI-CNVDQGSTELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSYFKLSTDSCPTHLAVLDEV 447
            |.: ||.::|:|||:|.|.|||.||::|||.:||::|::..|.||.||:|.||..|.|||:|||:
Zfish   383 HNLCCNENKGATELVAGLSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEI 447

  Fly   448 AAVHPTLQQQILFLLIRLFESKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYIKQCCAIE 512
            :..|..|..|:|.|||:|||::..:|:::.|:|:||.:|||||:||:||.|:||:.||::|....
Zfish   448 STCHQLLHPQVLQLLIKLFETEHSQLDVMEQMELKKTLLDRMVHLLSRGYVLPVVGYIRKCLEKL 512

  Fly   513 DTDISLIRYFVTEVLETITHPYSPEFVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHY 575
            :||||||||||||||:.|..||:.:|||||||::||:.|.||:|.||:||||:|||.|||:::
Zfish   513 NTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIRTEGENDPVAEFIAHCKSNF 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TH1	NP_573123.1	TH1	2..576	CDD:398497	313/583 (54%)
nelfcd	NP_957484.1	TH1	2..576	CDD:398497	313/583 (54%)