Protein Alignment TH1 and TH1

DIOPT Version :10

• Sequence 1: NP_573123.1
• Gene: TH1 / 32607
• FlyBaseID: FBgn0010416
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: XP_310712.4
• Gene: TH1 / 1271857
• VectorBaseID: AGAMI1_010385
• Length: 585
• Species: Anopheles gambiae
• Alignment Length: 585
• Identity: 447/585 - (76%)
• Similarity: 512/585 - (87%)
• Gaps: 7/585 - (1%)

  Fly     1 MEVEYDDSGWQGRAKGQTNPEETLE------DNPQKTIQECLEKFLTPDYIMEPGIFTQLKRYFQ 59
            ||.|::|..|...|.....|||.:|      :||:..:.:||:.|.:.|||||||||.|||||||
Mosquito     1 MEEEFEDEAWNNSAGRGNAPEEEVENHEEPSENPKAVVSDCLQLFSSVDYIMEPGIFVQLKRYFQ 65

  Fly    60 SGGSPEEVISMLSENYKAVAQMANLLAEWLILAGVKVTEVQAMVENHLKEMILKSFDPKKADTIF 124
            :||:||:||:.||.||.||||.|||||||||:|||:||:||||||||||:||||:|||||||.||
Mosquito    66 AGGTPEQVINTLSANYTAVAQTANLLAEWLIMAGVRVTDVQAMVENHLKDMILKTFDPKKADKIF 130

  Fly   125 TEEGETPDWLTEMIDHYTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQSEITSISTAAQQIEVF 189
            |||||||.||||||:|:||||||||||||||:|||||||||||||||||||||||||||||||||
Mosquito   131 TEEGETPGWLTEMIEHHTWRSLIYRLAEEYPECLMLNFTIKLISDAGFQSEITSISTAAQQIEVF 195

  Fly   190 SRVLKTSIVKFLNNPDDVHGAIQECARMVCHGQHTYVYSQVLIQVLSQEQKGGFNMKRLSQEIIK 254
            ||||||:|.|||::|:|..|||:|.|:||||||||||||||||||||||.||||.||||||||.|
Mosquito   196 SRVLKTAIAKFLSHPEDWQGAIEEVAKMVCHGQHTYVYSQVLIQVLSQEAKGGFIMKRLSQEITK 260

  Fly   255 YALQNNQNVTPITMALNGSAVYPQACQALTSMLTRNTLNPADITVLFRNYSGSDPPPIDLIRNPQ 319
            |||:||.||||||||||||:.:||||:||||||:||||||||||||:|||:..:|||||||||||
Mosquito   261 YALKNNHNVTPITMALNGSSRHPQACEALTSMLSRNTLNPADITVLYRNYTSPEPPPIDLIRNPQ 325

  Fly   320 FLELLVDALFRSGVKINPEHKPKYMFLLAYASAVIDQPAKK-RPMTERMLNKEELKSTIQAIEKA 383
            |||||||:||:.|||||.|||.||::||.||::|.:.|.|| :|...|:|||:|||:||.||||.
Mosquito   326 FLELLVDSLFKVGVKINQEHKSKYIYLLGYAASVCEIPTKKGQPKGHRVLNKDELKATIIAIEKV 390

  Fly   384 HTICNVDQGSTELIAELQTLYNCIKYPVVGVGVIRWIENVVMEPSYFKLSTDSCPTHLAVLDEVA 448
            |.||||.:||:||||::.|||:||::||||||||||:||.|.|||||||.|:|||.|||:|||||
Mosquito   391 HAICNVSRGSSELIADISTLYSCIRFPVVGVGVIRWVENTVTEPSYFKLCTESCPLHLALLDEVA 455

  Fly   449 AVHPTLQQQILFLLIRLFESKQDELEILVQLEMKKMILDRMVNLLTRGCVVPVLRYIKQCCAIED 513
            .||.:|..|||.||:|||||||||||||||||:|||:||||||||.|||||||::||.|||...|
Mosquito   456 CVHASLHDQILRLLVRLFESKQDELEILVQLELKKMLLDRMVNLLARGCVVPVVKYISQCCTRGD 520

  Fly   514 TDISLIRYFVTEVLETITHPYSPEFVQLFLPMVENEEITGTMRGEGDNDPVSEFIVHCKAHYTTV 578
            ||||||||||||||||:|||||.|||||||||||||||||:|||||||||||||||||||||||:
Mosquito   521 TDISLIRYFVTEVLETVTHPYSSEFVQLFLPMVENEEITGSMRGEGDNDPVSEFIVHCKAHYTTL 585

  Fly   579  578
            Mosquito   586  585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TH1	NP_573123.1	TH1	2..576	CDD:398497	443/580 (76%)
TH1	XP_310712.4	TH1	2..583	CDD:398497	446/584 (76%)