Protein Alignment exd and Pknox2

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001258207.1
• Gene: Pknox2 / 680549
• RGDID: 1590611
• Length: 475
• Species: Rattus norvegicus
• Alignment Length: 429
• Identity: 83/429 - (19%)
• Similarity: 132/429 - (30%)
• Gaps: 183/429 - (42%)

  Fly    60 EAQARKHTLNCHRMKPALFSVLCEIKEKTV------------LSIRN-----TQEEEP---PDPQ 104
            :.:|.|..:..|.:.| |.::|.|..|:..            :.|.|     .||.:|   .||:
  Rat    66 QLEADKRAVYRHPLFP-LLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPE 129

  Fly   105 LMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQE 169
               |||:::                                            |..|:.:|:..|
  Rat   130 ---LDNLMV--------------------------------------------KAIQVLRIHLLE 147

  Fly   170 LEKYEQACNEFTT----------HVMNLLREQ-----SRTRP----------------------- 196
            |||..:.|.:|..          |..||||..     |..:|
  Rat   148 LEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNN 212

  Fly   197 ----ITPKE----------------------------IERMVQIIHKKF--SSIQMQLKQSTCEA 227
                :.|..                            :....|::.:..  .:||:|..|...:.
  Rat   213 PQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDL 277

  Fly   228 VMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNK 292
            ..:|.:....::.||....|.|:.|:..:.:.||.:|||:|:.|.::|.:..:|:.||:|||.|.
  Rat   278 TSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINA 342

  Fly   293 RIRYKKNIGKAQEEANLYAAKK----------------AAGASPYSMAGPPSGTTTPMMSPAPPQ 341
            |.|..:.:..|........|||                |||.  ....|...||.
  Rat   343 RRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGV--LQQQGGTPGTN---------- 395

  Fly   342 DSMGYPMGSGGYDQQQPY--DNS--------MGGYDPNL 370
                 |.||...|..|..  ||:        |..:|.:|
  Rat   396 -----PDGSINLDNLQSLSSDNATMAMQQAMMAAHDDSL 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	41/268 (15%)
		homeodomain	239..299	CDD:238039	22/59 (37%)
Pknox2	NP_001258207.1	PLN02983	<3..>66	CDD:215533	83/429 (19%)
		Meis_PKNOX_N	96..181	CDD:465140	24/131 (18%)
		Homeobox_KN	307..345	CDD:428673	16/37 (43%)