Protein Alignment exd and meis3

DIOPT Version :10

• Sequence 1: NP_523360.1
• Gene: exd / 32567
• FlyBaseID: FBgn0000611
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001006782.1
• Gene: meis3 / 448474
• XenbaseID: XB-GENE-485337
• Length: 453
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 93/467 - (19%)
• Similarity: 151/467 - (32%)
• Gaps: 180/467 - (38%)

  Fly     9 AHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRM 73
            ||||  .|.|.:.||......:.|:.:.|.....:|            |.|..:..|..:..|.:
 Frog    25 AHTG--RALQHHSLSQSAPYGSTGAAHRVPMPPGMG------------SNDGLKREKDEIYGHPL 75

  Fly    74 KPALFSVL--CEI-----------------------KEKTVLSIRNTQEEEPPDPQLMRLDNMLI 113
            .|.|..|.  ||:                       .|...:..:..:.|:|.......||:::|
 Frog    76 FPLLALVFEKCELATCSPRDNSGSFPGGDVCSSDSFNEDIAVFAKQVRTEKPLFSSNPELDSLMI 140

  Fly   114 AEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACN 178
                                                        :..|:.:.:..||||....|:
 Frog   141 --------------------------------------------QAIQVLRFHLLELEKVHDLCD 161

  Fly   179 EFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQST--CEAVMILRSRF------ 235
            .|....:..|:.:   .||.        .:|..:..|.:..|:..|  |.::....:.:
 Frog   162 NFCHRYITCLKGK---MPID--------LVIDDRDGSSKSDLEDFTGSCTSLSDQNNSWIRDHDE 215

  Fly   236 ---------------------------------------------LDARRKRRN-----FSKQAS 250
                                                         || |.|:||     |.|.|:
 Frog   216 TGSTHSGTPGPSSGGLASQSGDNSSEQGDCMDNSVASPSTGDDDDLD-RDKKRNKKRGIFPKVAT 279

  Fly   251 EILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKA 315
            .|:..:.:.|||:||||||.|::||:..|:|:.||:|||.|.|   ::.:....:::|    :..
 Frog   280 NIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINAR---RRIVQPMIDQSN----RTG 337

  Fly   316 AGASPYSMAG-----------------PPSGTTTP-MMSPAPPQDSMGYPMGSGGYDQQQPYDNS 362
            .|.:|||..|                 ||.....| ..:.||....||:|  ..||....|..::
 Frog   338 QGGAPYSPDGQNMGGYVMDGQQHMGIRPPGFQGIPGDYTAAPSTMPMGFP--PAGYTPAIPPHSA 400

  Fly   363 MGGYDPNLHQDL 374
            ...:.|:||..|
 Frog   401 GLRHGPSLHSYL 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exd	NP_523360.1	PBC	42..237	CDD:461052	31/272 (11%)
		homeodomain	239..299	CDD:238039	29/64 (45%)
meis3	NP_001006782.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..64		7/42 (17%)
		Meis_PKNOX_N	102..186	CDD:465140	17/138 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..272		9/80 (11%)
		Homeobox_KN	286..324	CDD:428673	21/40 (53%)