Protein Alignment Lcch3 and Rdl

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 568
• Identity: 181/568 - (31%)
• Similarity: 277/568 - (48%)
• Gaps: 145/568 - (25%)

  Fly    39 NVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFN 103
            |::..:.:....||.|:|||:||.|:.||:.:.:.|..::|||.||:|:..|..|:|.|.|||:
  Fly    58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAY- 121

  Fly   104 IFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGM 168
                    ....|: :.|::..:|.:.||||||||.|:|.|:.|..|..|:.:|:...|::|..:
  Fly   122 --------RKRPGV-ETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSI 177

  Fly   169 RFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKP--TPVRGVEDAELPQFTIIGYET 231
            |.|.|.:|.|:|.|:|:|.|.|.:||||:|||:.|:..:|:.  :.|....:.|||||.::|:..
  Fly   178 RLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQ 242

  Fly   232 NDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTV 296
            ...:..|.||.|.||:...:..|::||::.|.|:||.|||::||||||:|..||.||||||:|||
  Fly   243 RATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTV 307

  Fly   297 LTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKK-KIKKVKECC 360
            |||||:.:...::||:|||||:||:||..|||.|||:|||||.|.|     .||: :::|.:...
  Fly   308 LTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY-----MAKRIQMRKQRFMA 367

  Fly   361 PGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFP-----PSFR 420
            ..||.:.::.:.....:.       :.:|.|       ||.:...|    .:|..|     |...
  Fly   368 IQKIAEQKKQQLDGANQQ-------QANPNP-------NANVGGPG----GVGVGPGGPGGPGGG 414

  Fly   421 ITRNYGTG-------------HSQLRRRA-QRGISTRPRMLHALK-----RGASAI--------- 457
            :....|.|             ||.....| ::.:|.||.....::     ||.|.:
  Fly   415 VNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRF 479

  Fly   458 ----------------------------------------------------------KATIP-- 462
                                                                      :|.:|
  Fly   480 KVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAH 544

  Fly   463 --------KIKDVN--------IIDKYSRMIFPISFLAFNLGYWLFYI 494
                    |:||:|        .||||||::||:.|:.|||.||:.|:
  Fly   545 LLHPGKVKKVKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	180/565 (32%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	69/192 (36%)
		Cys-loop	185..199	CDD:349809	7/13 (54%)
		Neur_chan_memb	274..588	CDD:460753	95/336 (28%)