Protein Alignment Lcch3 and nAChRbeta1

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 82/337 - (24%)
• Similarity: 140/337 - (41%)
• Gaps: 43/337 - (12%)

  Fly    33 LAGRLENVTQTISNILQGYDIRLRP--NFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYW 95
            |....|:..:.:.::.:||:..:||  |. .:.:.|...|.......::|.|......::|...|
  Fly    21 LVSASEDEERLVRDLFRGYNKLIRPVQNM-TQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVW 84

  Fly    96 RDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGG 160
            .|.:|.:        ||.|.|...||.|..|   |:|.||....|:.:.......:.|.|:...|
  Fly    85 YDYQLQW--------DEADYGGIGVLRLPPD---KVWKPDIVLFNNADGNYEVRYKSNVLIYPTG 138

  Fly   161 DGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESY---GYTVS----------DVVMYWKPTP 212
            :  |.:........:|.:|:.|:|.|.|.|.::..|:   |..||          |:..|||
  Fly   139 E--VLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVDLSDYWK--- 198

  Fly   213 VRGVED-AELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWV 276
             .|..| .|:|.:..: || .|......|.:    :....::|...::.....||::||..|..:
  Fly   199 -SGTWDIIEVPAYLNV-YE-GDSNHPTETDI----TFYIIIRRKTLFYTVNLILPTVLISFLCVL 256

  Fly   277 SFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYV-KAIDIYLVMCFVF-VFAALLEYAA 339
            .|::..|| ..:|.|||:.:|::......|...||..|.| ..|..||:..|:. ..:.|:....
  Fly   257 VFYLPAEA-GEKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVII 320

  Fly   340 VNYTYWGKRAKK 351
            :|:.:.|.|..:
  Fly   321 INWNFRGPRTHR 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	82/337 (24%)
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:455710	82/337 (24%)
		LGIC_ECD_nAChR_proto_beta-like	27..236	CDD:349833	54/232 (23%)
		Cys-loop	152..166	CDD:349833	6/13 (46%)