Protein Alignment Lcch3 and lgc-38

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001355511.1
• Gene: lgc-38 / 3565717
• WormBaseID: WBGene00017389
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 468
• Identity: 177/468 - (37%)
• Similarity: 256/468 - (54%)
• Gaps: 53/468 - (11%)

  Fly    39 NVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFN 103
            |||:.:..::..:|.|:|||:||.|:.|.:...:.:..|:|||:||||:.:||.|.|:|.|||:
 Worm    51 NVTRLLDKLIASHDRRIRPNYGGPPIEVNITAHVTTISAVSEVSMDYTLDLYLRQIWKDPRLAW- 114

  Fly   104 IFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGM 168
                    |:|  :.|.||:..|..:.||.|||||.|:|.||.|:.|..|..:|:...|.|...:
 Worm   115 --------ESD--VEDSLTIGIDMVKTIWTPDTFFPNEKKSFFHEATSHNSFLRIDNHGNVLRSI 169

  Fly   169 RFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGV-EDAELPQFTIIGYETN 232
            |.|.|..|.|.||.:|||.|.|.:|:|||||:..|::.:|..|....: |:..|..|||..::..
 Worm   170 RLTVTANCPMSLHTFPLDRQECALEVESYGYSTKDIIYHWHGTNAVTIDENVHLAHFTIGEHKHI 234

  Fly   233 DRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVL 297
            :|...|:||.|.||:..|..:||||:::.|.|.||.|||::||||||:|.||..||||:|:||||
 Worm   235 ERTISLSTGNYSRLTAYFLFKRNIGFYLIQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVL 299

  Fly   298 TMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPG 362
            ||||:.|...:|||::||||::|::|.:||..|||:||||||:.|      ..|:.:.|....|.
 Worm   300 TMTTLMTSTNASLPKVSYVKSLDVFLGVCFFIVFASLLEYAAIGY------LMKRNRSVPAASPV 358

  Fly   363 KIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGT 427
            :..:         ||:..|:|     ..|...||..|.....:..|.        |.:.:||  .
 Worm   359 QYYE---------TEEFFEIQ-----CHPKFVRGAINYCDGVLKREA--------SRKKSRN--R 399

  Fly   428 GHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKI--KDVN---------IIDKYSRMIFPIS 481
            ..|.::......|..||...|..:|........:|.|  |..|         .:|.:||..|||.
 Worm   400 RDSSMKNYQNNNIHHRPSDGHVDQRIPLLSMVPMPPIPFKPQNGAWGKVRPAQVDLFSRFAFPIF 464

  Fly   482 FLAFNLGYWLFYI 494
            |:.|::.||.:||
 Worm   465 FVIFHIVYWTYYI 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	175/465 (38%)
lgc-38	NP_001355511.1	LIC	42..476	CDD:455710	175/465 (38%)
		LGIC_ECD_GABAR_RDL-like	76..257	CDD:349809	74/191 (39%)
		Cys-loop	177..191	CDD:349809	8/13 (62%)