Protein Alignment Lcch3 and Gabra5

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_058991.2
• Gene: Gabra5 / 29707
• RGDID: 61859
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 166/467 - (35%)
• Similarity: 230/467 - (49%)
• Gaps: 78/467 - (16%)

  Fly    41 TQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIF 105
            |:.:..:|.|||.||||..|.....|..|:.:.||..:|:..|:|||.::..|.|:||||.|.
  Rat    50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFK-- 112

  Fly   106 GQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRF 170
                      |....|.|:...|.|||.|||||.|.|.|..|::|..|||:||..||.:.|.||.
  Rat   113 ----------GPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRL 167

  Fly   171 TTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDAE----LPQFTIIGYET 231
            |.:..|.|.|..:|:|:..|.::..||.|..|:||..|.....:.|..||    |.|:.::|...
  Rat   168 TISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTV 232

  Fly   232 NDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTV 296
            .......:||.|..::..|.|:|.|||||.|||||.|:.|:||.||||:|.|:..||...|:|||
  Rat   233 GTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 297

  Fly   297 LTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNY---TYWGKRAKKKIKKVKE 358
            |||||:|...|:|||:::|..|:|.::.:|:.|||:||:|:|.|||   ..|....||.::
  Rat   298 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALE---- 358

  Fly   359 CCPGKIGKSER------SETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPP 417
              ..||.|.||      |....||..:....::....:|.   ||.||    :||.:
  Rat   359 --AAKIKKKERELILNKSTNAFTTGKLTHPPNIPKEQLPG---GTGNA----VGTAS-------- 406

  Fly   418 SFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISF 482
                                         :.|.:...|..|.|   ...::.|||.||::|||.|
  Rat   407 -----------------------------IRASEEKTSESKKT---YNSISKIDKMSRIVFPILF 439

  Fly   483 LAFNLGYWLFYI 494
            ..|||.||..|:
  Rat   440 GTFNLVYWATYL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	165/464 (36%)
Gabra5	NP_058991.2	LIC	15..450	CDD:455710	165/464 (36%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	76/209 (36%)
		Cys-loop	173..187	CDD:349839	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..414		8/75 (11%)