Protein Alignment Lcch3 and acc-1

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001293865.1
• Gene: acc-1 / 177799
• WormBaseID: WBGene00010275
• Length: 470
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 127/471 - (26%)
• Similarity: 234/471 - (49%)
• Gaps: 67/471 - (14%)

  Fly    39 NVTQTISNILQ-GYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAF 102
            |.|:.|:.:|: .|:....|:   .|.||.:|:.:....::||:..|:.|.:|:|::|.|..|.:
 Worm    36 NDTEIINALLKDSYNKHYIPS---HPTHVRVDMWVQEVTSVSELTQDFEIDLYINEFWEDPALVY 97

  Fly   103 --------NIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLG 159
                    ||   .|||:       ||       :::|:|:|.|.|.|::.:|:...:|..:.:.
 Worm    98 EDMNPCKRNI---SFDDK-------VL-------QRLWLPNTCFINSKSAAIHESPFKNVFLMVF 145

  Fly   160 GDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYW-KPTPVRGVEDAELPQ 223
            .:|.:....|...|..|.|.|..:|.|.|.|.:..||:.|...:|.|.| :|.||..::..|||.
 Worm   146 SNGTLWTNYRMKLTGPCDMKLKRFPFDKQKCYLTFESFNYNTGEVRMQWNQPYPVILLKRIELPD 210

  Fly   224 FTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSAR 288
            |.::.:.....::....|.:..|:::|..:|..|::|.|.|:|:::.:::||:||::...|..||
 Worm   211 FKLVNFSVIAVEQMYPAGWWDELTVAFVFERRYGWYVLQGYIPTMVTIVISWISFYLGPRAIPAR 275

  Fly   289 VALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKI 353
            ..||:.::|.||.....:..:|||:|||||||::::...:|:|.:|||.|.|.:
 Worm   276 TMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWMLSGMLFIFLSLLELAVVGF----------- 329

  Fly   354 KKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPP- 417
            ....|..|.|:.|.:|.|   ..::....:.::.||...||:...:..::|:    .|....||
 Worm   330 MSRNEGLPPKVKKRKRQE---DDDEGFSWKSMQTSPHLELRQFWVDKRVNSL----RNDSAVPPV 387

  Fly   418 ----SFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIF 478
                ...:.:.|   .:..:||.:|      :.:..|::...|::...|:     .:|.||.:.|
 Worm   388 EDYAPMELEQPY---QNITKRREKR------KWMSGLRKKWRAMRELRPE-----TVDFYSAIFF 438

  Fly   479 PISFLAFNLGYWLFYI 494
            |.:::.||:.||.||:
 Worm   439 PTAYMLFNISYWSFYL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	125/468 (27%)
acc-1	NP_001293865.1	LIC	39..453	CDD:455710	123/465 (26%)
		LGIC_ECD_GABAAR	59..242	CDD:349791	53/199 (27%)
		Cys-loop	162..176	CDD:349791	6/13 (46%)