Protein Alignment Lcch3 and Gabrg3

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 524
• Identity: 169/524 - (32%)
• Similarity: 251/524 - (47%)
• Gaps: 105/524 - (20%)

  Fly    18 LGAQLQLIRCI----------------------RKDVLAGRLE--NVTQTISNILQGYDIRLRPN 58
            :.|:|.|:.|:                      :|.|||.:.:  :||..::.:|:.||.:|||:
Mouse     1 MAAKLLLLLCLFSGLHARSRRVEEDENEDSPSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRPD 65

  Fly    59 FGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTL 123
            .|.:|..:.:|:.:.|...:|.:||:|.|.::..|.|.|.||.||            ....:|||
Mouse    66 IGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN------------STMKILTL 118

  Fly   124 SGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQ 188
            :.:....||:|||.|.|.|.:..|.:|..|:|:|:..||.:.|.:|.|....|.:.||.:|:|:.
Mouse   119 NSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDAH 183

  Fly   189 NCTVEIESYGYTVSDVVMYWKPTPVRGVEDA--ELPQFTIIGYETNDRKERLATGVYQRLSLSFK 251
            .|.:...||||...:::..|:...|...:..  .|.||..:|..........:.|.|..:::.|:
Mouse   184 ACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFE 248

  Fly   252 LQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYV 316
            |.|.:|||..|||:|.||.|:||||||||..:||.||..|||||||||||:||..|.||||:|||
Mouse   249 LSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYV 313

  Fly   317 KAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIE 381
            .|:|:::.:||:||||||:|||.:|  |:....|..|:|.|                  |..::.
Mouse   314 TAMDLFVTVCFLFVFAALMEYATLN--YYSSCRKPTIRKKK------------------TSQLLH 358

  Fly   382 LQDVRMSPIP-SLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLR------------ 433
            ....|..|.. ||:..:..:.||.         :.||...||.|......:..
Mouse   359 PDSTRWIPDRISLQAPSNYSLLDM---------RPPPPVMITLNNSMYWQEFEDTCVYECLDGKD 414

  Fly   434 --------RRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYW 490
                    ...:.|         :.:||...|        ||:.:|.|||:.||.|||.|||.||
Mouse   415 CQSFFCCYEECKSG---------SWRRGRIHI--------DVSELDSYSRVFFPTSFLLFNLVYW 462

  Fly   491 LFYI 494
            :.|:
Mouse   463 VGYL 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	168/521 (32%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:455710	158/472 (33%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	55/192 (29%)
		Cys-loop	171..185	CDD:349801	5/13 (38%)