Protein Alignment Lcch3 and Gabrg2

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_032099.1
• Gene: Gabrg2 / 14406
• MGIID: 95623
• Length: 474
• Species: Mus musculus
• Alignment Length: 472
• Identity: 167/472 - (35%)
• Similarity: 240/472 - (50%)
• Gaps: 79/472 - (16%)

  Fly    39 NVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFN 103
            :||..::|:|:|||.:|||:.|.:|..:..|:.:.|...::.:||:|||.::..|.|.|.||.||
Mouse    64 DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 128

  Fly   104 IFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGM 168
                        ....||.|:.:...|||:|||||.|.|.:..|.:|..|:::|:..||.|.|.:
Mouse   129 ------------STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTL 181

  Fly   169 RFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDA---ELPQFTIIGYE 230
            |.|....|.:.||.:|:|..:|.:|..||||...::|..||.:.|. |.|.   .|.||:.:|..
Mouse   182 RLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVE-VGDTRSWRLYQFSFVGLR 245

  Fly   231 TNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITT 295
            ......:..:|.|..:|:.|.|.|.:|||..|||:|..|||:|||||||||.:|..||.:|||||
Mouse   246 NTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 310

  Fly   296 VLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKR-AKKKIKKVKEC 359
            ||||||:||..|.|||::|||.|:|:::.:||:|||:||:||..::|....:: :|.|.||.|.
Mouse   311 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKN- 374

  Fly   360 CPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRRGTYNA-TLDSIGTETMNLGKFPPSFRITR 423
                                           |.||..::.| |:|.          .|.|..|..
Mouse   375 -------------------------------PLLRMFSFKAPTIDI----------RPRSATIQM 398

  Fly   424 NYGTGHSQLRRRAQRGISTRPR--------MLHALKRGA---SAIKATIPKIKDVNIIDKYSRMI 477
            |..| |.| .|..:.|......        .....:.||   ..|...|.|      :|.|:|:.
Mouse   399 NNAT-HLQ-ERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAK------MDSYARIF 455

  Fly   478 FPISFLAFNLGYWLFYI 494
            ||.:|..|||.||:.|:
Mouse   456 FPTAFCLFNLVYWVSYL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	166/469 (35%)
Gabrg2	NP_032099.1	LIC	68..471	CDD:455710	164/465 (35%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	63/193 (33%)
		Cys-loop	189..203	CDD:349801	5/13 (38%)