Protein Alignment Lcch3 and Gabrg1

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 511
• Identity: 176/511 - (34%)
• Similarity: 251/511 - (49%)
• Gaps: 99/511 - (19%)

  Fly    13 LFFFLLGAQLQLIRCIRKD--------------VLAGRLE--NVTQTISNILQGYDIRLRPNFGG 61
            |.|.||  .|.|..|:.|.              |||.::.  ::||.::::|||||.:|||:.|.
Mouse    23 LIFLLL--TLHLGNCVDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGV 85

  Fly    62 EPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGD 126
            .|..:..|:.:.|...:..:||:|||.:...|.|.|.||.||            ....||.|:.:
Mouse    86 RPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFN------------STMKVLMLNSN 138

  Fly   127 FAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCT 191
            ...|||:|||||.|.:.|..|.:|..|:|:|:..||.|.|.:|.|....|.:.||.:|:|..:|.
Mouse   139 MVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCP 203

  Fly   192 VEIESYGYTVSDVVMYWKPTPVRGVEDAE---LPQFTIIGYETNDRKERLATGVYQRLSLSFKLQ 253
            :|..||||..:::...||...|. |.|.:   |.||..:|...:.......:|.|..:::.|.|.
Mouse   204 LEFSSYGYPKNEIEYKWKKPSVE-VADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLS 267

  Fly   254 RNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKA 318
            |.:|||..|||:|.||.|:|||||||||.:|..||.:|||||||||||:||..|.|||::|||.|
Mouse   268 RRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTA 332

  Fly   319 IDIYLVMCFVFVFAALLEYAAVNYTYWGKRAK----KKIKKVKECCPGKIGKSERSETCSTTEDI 379
            :|:::.:||:||||||:||..::|.....:.|    :|:|......||....|          .:
Mouse   333 MDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRGRKLKNKTSASPGLHAGS----------TL 387

  Fly   380 IELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRI------TRNYGTGHSQLRRRAQR 438
            |.:..:      ||.:|.     |..|.:.:. ||...||..      |.::..|...:|
Mouse   388 IPMNSI------SLPQGE-----DDYGYQCLE-GKDCTSFFCCFDDCRTGSWREGRIHIR----- 435

  Fly   439 GISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
                                  |.|      ||.|||:.||.:|..|||.||:.|:
Mouse   436 ----------------------IAK------IDSYSRIFFPTAFALFNLVYWVGYL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	174/506 (34%)
Gabrg1	NP_034382.2	LIC	66..462	CDD:455710	163/463 (35%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	62/193 (32%)
		Cys-loop	188..202	CDD:349801	5/13 (38%)