Protein Alignment Lcch3 and gabrg3

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002931686.2
• Gene: gabrg3 / 100494037
• XenbaseID: XB-GENE-6041774
• Length: 446
• Species: Xenopus tropicalis
• Alignment Length: 496
• Identity: 169/496 - (34%)
• Similarity: 242/496 - (48%)
• Gaps: 76/496 - (15%)

  Fly    15 FFLLGAQLQLIRCIRKD-----------VLAGRLENVTQT--ISNILQGYDIRLRPNFGGEPLHV 66
            ||||.......|.|..|           |||.:.::...|  ::.:|:.||.:|||:.|.:|..:
 Frog     9 FFLLSVFQACSRKIEDDEYEDLTMNQKWVLAPKTQDTDATLILNKLLKEYDKKLRPDIGIKPTVI 73

  Fly    67 GMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKI 131
            .:|:.:.|...:|.:||:|.|.::..|.|.|.||.||            ....:|||:.:....|
 Frog    74 DVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN------------STMKILTLNSNMVGLI 126

  Fly   132 WVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIES 196
            |:|||.|.|.|.:..|.:|..|:|:|:..||.:.|.:|.|....|.:.||.:|:|..:|.:...|
 Frog   127 WIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSS 191

  Fly   197 YGYTVSDVVMYWKPTPVRGVEDA--ELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYF 259
            |||...::|..|:...|......  .|.||..:|........:.:.|.|..:::.|.|.|.:|||
 Frog   192 YGYPREEMVYRWRKNSVETANQKSWRLYQFDFMGLRNTTEIVKTSAGDYIVMTVYFDLSRRMGYF 256

  Fly   260 VFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLV 324
            ..|||:|.||.|:||||||||..:||.||.||||||||||||:||..|.||||:|||.|:|:::.
 Frog   257 TIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVT 321

  Fly   325 MCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCSTTEDIIELQDVRMSP 389
            :||:||||||:||||:||             ...|...:..|.::|.        ..:.|:|..|
 Frog   322 VCFLFVFAALIEYAALNY-------------YSSCKKPRCTKKKKSN--------YSVLDMRPPP 365

  Fly   390 -IPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRG 453
             :.:|....|....:.........||...||...  |....|...||.:         :|.
 Frog   366 TVITLNNSLYWQEFEEACVYECLDGKDCQSFFCC--YDECKSGSWRRGR---------IHI---- 415

  Fly   454 ASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYI 494
                        |:..:|.|||:.||.|||.|||.||:.|:
 Frog   416 ------------DLLELDSYSRVFFPTSFLLFNLVYWVGYL 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	168/493 (34%)
gabrg3	XP_002931686.2	LIC	50..443	CDD:455710	157/452 (35%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	56/192 (29%)
		Cys-loop	171..185	CDD:349801	5/13 (38%)