Protein Alignment Lcch3 and gabra1

DIOPT Version :10

• Sequence 1: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_031754594.1
• Gene: gabra1 / 100490334
• XenbaseID: XB-GENE-6033338
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 471
• Identity: 168/471 - (35%)
• Similarity: 238/471 - (50%)
• Gaps: 88/471 - (18%)

  Fly    41 TQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIF 105
            |:.:..:|.|||.||||..|.....|..|:.:.||..:|:.:|:|||.::..|.||||||.|.
 Frog    42 TRILDRLLDGYDNRLRPGLGERVTEVNTDIFVTSFGPVSDHDMEYTIDVFFRQGWRDERLKFK-- 104

  Fly   106 GQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRF 170
                      |...||.|:...|.|||.|||||.|.|.|..|::|..|||:|:..||.:.|.||.
 Frog   105 ----------GPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRL 159

  Fly   171 TTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDAE----LPQFTIIGYET 231
            |....|.|.|..:|:|:..|.::..||.||.::||..|...|...|..||    |.|:.::|...
 Frog   160 TVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYSWTREPSLSVVVAEDGSRLNQYDLLGQTV 224

  Fly   232 NDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTV 296
            .....:.:||.|..::..|.|:|.|||||.|||||.|:.|:||.||||:|.|:..||...|:|||
 Frog   225 ASGIVQSSTGEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 289

  Fly   297 LTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVN------YTYWGKR-AKKKIK 354
            |||||:|...|:|||:::|..|:|.::.:|:.|||:||:|:|.||      |.:.||. ..:|.|
 Frog   290 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPK 354

  Fly   355 KVKECCPGKIGKSERSETCSTTEDIIELQDVRMSPIPSLRR-GTYNATLDSIGTETMNLGKFPPS 418
            |||:                                |.::: .||       .:.|.|   :||:
 Frog   355 KVKD--------------------------------PLIKKNNTY-------ASATAN---YPPT 377

  Fly   419 FRITRNYGTGHSQLRRRA---QRGISTRPRMLHALKRGASAIKATIPK--IKDVNIIDKYSRMIF 478
              |.|:  .|.:.:.:.|   .:.|..:|             |...||  ...|:.||:.||:.|
 Frog   378 --IPRD--PGLATIAKSATIEPKDIEPKP-------------KPAEPKKTFNSVSKIDRLSRIAF 425

  Fly   479 PISFLAFNLGYWLFYI 494
            |:.|..|||.||..|:
 Frog   426 PLLFGTFNLVYWATYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	167/468 (36%)
gabra1	XP_031754594.1	LIC	11..440	CDD:455710	167/468 (36%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	75/204 (37%)
		Cys-loop	165..179	CDD:349835	5/13 (38%)