DRSC/TRiP Functional Genomics Resources

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Protein Alignment CycD and CLB5

DIOPT Version :10

Sequence 1:NP_523355.2 Gene:CycD / 32551 FlyBaseID:FBgn0010315 Length:477 Species:Drosophila melanogaster
Sequence 2:NP_015445.1 Gene:CLB5 / 856237 SGDID:S000006324 Length:435 Species:Saccharomyces cerevisiae


Alignment Length:437 Identity:98/437 - (22%)
Similarity:172/437 - (39%) Gaps:109/437 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 LYRLNKRQQQMSSPAIIRDQSSICS----------------SLGDAESDSHPDAQNNAVVCNMKE 65
            :|..|:||...|:..|::::.::..                :|.|...:::|.:||..:|...| 
Yeast    17 IYNENERQLCNSNLKILQNKRALSKNDSSSKQQVQDSKPRRALTDVPVNNNPLSQNKRIVAGSK- 80

  Fly    66 LVYIYASVDSAAK--NPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTT 128
                      |||  ..|.:.          |..:|.|..|.|....:.|      |..:|....
Yeast    81 ----------AAKVRREENIR----------PIVSAVQKRQIYNDRTAAE------QEEEEEEEG 119

  Fly   129 TADPPAT----------DNVNTAIG----------DPTLYSDRCLENFLKVEEKH-HKIPDTYFS 172
            ..|..|:          :.|:..:|          |..:.::...|.|..:..:. ..:|...:.
Yeast   120 EDDDAASIVNKKRRIDAEGVSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYL 184

  Fly   173 IQKD----ITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLL 233
            :.|.    :.|.||.|:.:|::||..:..|..|.:.|::|.|||||:...|...:||:||...|.
Yeast   185 LDKTSKYYLRPSMRTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLF 249

  Fly   234 LASKLREPSCRALSVDLLVVY---TDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRL 295
            :|:|..|     :::..|..|   ||.:..|:|:...|:::|:.|.:::....||:||.    |:
Yeast   250 IAAKFEE-----VNLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLR----RI 305

  Fly   296 PIGSKNFP-DINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASS--IAASM---------NGLK 348
            .......| :.||||.      .:..|...|:|.....||::|.:  ||..|         ||..
Yeast   306 SKADDYDPVNRNIGKF------ILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRNKNELWNGTL 364

  Fly   349 WHLRSG----HNLHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSR 391
            .|...|    |:..| .||..||..    .:.....|::.:..::.:
Yeast   365 QHYSGGIDPIHDEAF-QSLCIDLVK----DIASSKTHLDSLILKYKK 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CycDNP_523355.2 CYCLIN_SF 144..278 CDD:477360 39/141 (28%)
CYCLIN_CCND_rpt2 283..387 CDD:410220 30/119 (25%)
CLB5NP_015445.1 COG5024 1..431 CDD:227357 98/437 (22%)

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