Protein Alignment CycD and CLB2

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_015444.1
• Gene: CLB2 / 856236
• SGDID: S000006323
• Length: 491
• Species: Saccharomyces cerevisiae
• Alignment Length: 432
• Identity: 95/432 - (21%)
• Similarity: 173/432 - (40%)
• Gaps: 101/432 - (23%)

  Fly    14 DPSLYRLNKRQQQMSSPAIIRDQSSICSSLGDAESDSHPDAQNNAVVCNMKELV----------- 67
            |||       .||..:...|::        |.||..::...|.::   :.||::
Yeast   104 DPS-------SQQFGALTSIKE--------GRAELPANISLQESS---SAKEIIQHDPLKGVGSS 150

  Fly    68 --YIYASVDSAAKNP--EQLEPPPPPPPPPPPPPTATQSIQSYP--RYISQEPPTSH--CQRLDE 124
              .::.||::...:|  .||:        .....:.|.|.:..|  ..:.||.|...  |....:
Yeast   151 TEVVHNSVENEKLHPARSQLQ--------VRNTESETDSGKKRPISTIVEQELPKKFKVCDENGK 207

  Fly   125 RLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDI-----TPPMRKI 184
            ......|..|.|     :.||.:.|:...:.|    |..|::.......::|:     ....|.|
Yeast   208 EEYEWEDLDAED-----VNDPFMVSEYVNDIF----EYLHQLEVITLPKKEDLYQHRNIHQNRDI 263

  Fly   185 VAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLRE---PSCRAL 246
            :..|::::..:.....|.:.||:|.|||||..:.|:..:||::..:||.:|||..|   ||.:..
Yeast   264 LVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHF 328

  Fly   247 SVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVR 311
            :.:     ||.:..:|::.:.|.::|..|.::|:...|::||..:        ....|.:| :.|
Yeast   329 ASE-----TDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRI--------SKADDYDI-QSR 379

  Fly   312 GHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGL---KWHLRSGHNLHFLLSLMTDLTSVEQA 373
            ..|:..:.::..:.:|.....|..||:::..|...|   ||   .|:.:|:    ....|..|.|
Yeast   380 TLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGKGKW---DGNLIHY----SGGYTKEELA 437

  Fly   374 QVRDCMLHMEDIFKEHSRNLEPFLVN-IDPKEMSTLYYKRRF 414
            .|  |.:.|:            :||: |...|....|..|||
Yeast   438 PV--CHMIMD------------YLVSPIVHDEFHRKYQSRRF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	36/141 (26%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	23/106 (22%)
CLB2	NP_015444.1	COG5024	8..487	CDD:227357	95/432 (22%)