Protein Alignment CycD and CLN3

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_009360.1
• Gene: CLN3 / 851191
• SGDID: S000000038
• Length: 580
• Species: Saccharomyces cerevisiae
• Alignment Length: 259
• Identity: 49/259 - (18%)
• Similarity: 102/259 - (39%)
• Gaps: 43/259 - (16%)

  Fly   139 NTAIGDPTLYSDRCLENFLKVEEKHHKIPD-TYFSIQKDITPPMRKIVAEWMMEVCAEENCQEEV 202
            ::||.:   |::..|:::.::......:.: |.|:.|..:.|.||.::.:::|......|.....
Yeast    67 HSAISE---YNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTST 128

  Fly   203 VLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKW 267
            :.|....:|::.|...::....|:|:...|.::||..:...|..::.:|.....|..........
Yeast   129 LFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTM 193

  Fly   268 ELYVLSRLGWDL---------------SSVTPLD-----------FLE--LLMMRLPIG------ 298
            |:::...|.|.:               .|.:||.           |::  |.::....|
Yeast   194 EMHLFKSLDWSICQSATFDSYIDIFLFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKS 258

  Fly   299 -SKNFPDINIGKVRGHAQAFISLAAKEHKFA-KFSASTIAASS---IAASMNGLKWHLRSGHNL 357
             |...|.:||.:::..|.....||:...:.: |:..|.||..:   |..|:|....:|....||
Yeast   259 SSSQGPSLNINEIKLGAIMLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENINL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	23/134 (17%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	22/99 (22%)
CLN3	NP_009360.1	COG5024	35..576	CDD:227357	49/259 (19%)