Protein Alignment CycD and ccnd1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001005452.1
• Gene: ccnd1 / 448045
• XenbaseID: XB-GENE-6077306
• Length: 291
• Species: Xenopus tropicalis
• Alignment Length: 348
• Identity: 126/348 - (36%)
• Similarity: 184/348 - (52%)
• Gaps: 75/348 - (21%)

  Fly   136 DNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPD-TYFS-IQKDITPPMRKIVAEWMMEVCAEENC 198
            |.:..|..|..|.:||.|:..||.||.  ..|: :||. :||:|.|.||||||.||:|||.|:.|
 Frog     9 DTIRRAHLDRNLITDRVLQTMLKAEET--CCPNVSYFKCVQKEILPHMRKIVATWMLEVCEEQKC 71

  Fly   199 QEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDD 263
            :|||..||:||:|||||.|::||:|||:|.|.|:.||||::|..  .|:.:.|.:||||||..::
 Frog    72 EEEVFPLAMNYLDRFLSVKTLRKSQLQLLGATCMFLASKMKETI--PLTAEKLCIYTDNSIRPEE 134

  Fly   264 LIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFA 328
            |:..||.:|::|.|||:||||.||:|..:.::|: :::...|    :|.|||.|::|.|.:.||.
 Frog   135 LLLMELLILNKLKWDLASVTPHDFIEHFLNKMPL-TEDTKQI----IRKHAQTFVALCATDIKFI 194

  Fly   329 KFSASTIAASSIAASMNGLKWHLRSGHNLHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNL 393
            ....|.|||.|:||::.||        ||.                      :.:.:|.  ::.|
 Frog   195 SNPPSMIAAGSVAAAVQGL--------NLG----------------------NADSVFS--TQRL 227

  Fly   394 EPFL---VNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPH 455
            ..||   :..||..:      |..| .|.:.|.:.|:|             |.|||||..|
 Frog   228 TLFLSQVIKCDPDCL------RACQ-EQIESLLESSLR-------------QAQQQHNTSS---- 268

  Fly   456 RTHTCKMQAQAQ---AQNEIQDV 475
              .|..|..:|.   ...:::||
 Frog   269 --DTKNMVEEADISCTPTDVRDV 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	68/135 (50%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	27/103 (26%)
ccnd1	NP_001005452.1	CYCLIN_SF	1..149	CDD:477360	70/143 (49%)
		CYCLIN_CCND1_rpt2	154..263	CDD:410279	41/165 (25%)