Protein Alignment CycD and CycA

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 98/432 - (22%)
• Similarity: 171/432 - (39%)
• Gaps: 86/432 - (19%)

  Fly    53 DAQNNAVV--CNMKELVYIYASVDSAAKNPEQLEPPPPPPPPPPPPPTATQS----IQSYPRYIS 111
            |.:|:.|.  ...||||            ...|:..|........|.:..:|    |||....:.
  Fly   122 DKENHDVKFGAGQKELV------------DYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVG 174

  Fly   112 QEPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKD 176
            .|...|...|:.|.      ||..|.....  :...|....||.|.:.|:||...| .|...|||
  Fly   175 TETGVSPTGRVKEL------PPRNDRQRFL--EVVQYQMDILEYFRESEKKHRPKP-LYMRRQKD 230

  Fly   177 ITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLRE- 240
            |:..||.|:.:|::||..|.....|.:.|::.|:|||||..:|.:::||::..|.:.:|:|..|
  Fly   231 ISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEI 295

  Fly   241 -PSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSK-NFP 303
             |.    .|...|..||:|..|..:::.|..:|..|.:||.:.|...|:....:...:..| .:.
  Fly   296 YPP----EVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYM 356

  Fly   304 DINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMN--GLK-WHLRSGHNLHFLLSLMT 365
            .:.|.:        :||...| .:.::..|.::::|:|.:.:  |:: |..|           :.
  Fly   357 TLYISE--------LSLMEGE-TYLQYLPSLMSSASVALARHILGMEMWTPR-----------LE 401

  Fly   366 DLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPL 430
            ::|:.:...::..:||:....|             ..||::|...:.::.            |..
  Fly   402 EITTYKLEDLKTVVLHLCHTHK-------------TAKELNTQAMREKYN------------RDT 441

  Fly   431 PLPKAPAECVEQHQQQHNFGSAAPHRTHTCKMQAQAQAQNEI 472
            ....|..|.||  ..:.:|....  ..:.||.:.....|.:|
  Fly   442 YKKVAMMESVE--MSKDDFDQLC--EAYNCKQKEDEHQQPDI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	45/135 (33%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	16/107 (15%)
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	45/131 (34%)
		Cyclin_C	334..450	CDD:397230	22/160 (14%)