Protein Alignment CycD and Ccne2

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001102126.1
• Gene: Ccne2 / 362485
• RGDID: 1307783
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 76/311 - (24%)
• Similarity: 128/311 - (41%)
• Gaps: 60/311 - (19%)

  Fly    91 PPPPPPPTATQSIQSYPRYISQE--------------------PPT-----SHCQRLD--ERLTT 128
            |..|..|...|.||:..|..:|:                    ||.     |.|..::  .:...
  Rat    17 PNQPDSPQEAQIIQAKKRKTAQDVKKRTEEITKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIG 81

  Fly   129 TADPPATDNV---NTAIGDPTL------YSDRCLENFLKVEEKHHKIPDTYFSI-QKDITPPMRK 183
            |:|.....|.   |..|....|      .|....:|.|:.|.::  :.|.:|.: ..|:.|.||.
  Rat    82 TSDFSRFTNYRFKNLFINPSPLPDLSWACSQEVWQNMLQKESRY--VHDKHFEVLHSDLEPQMRS 144

  Fly   184 IVAEWMMEVCAEENCQEEVVLLALNYMDRF-LSSKSVRKTQLQILAAACLLLASKLREPSCRALS 247
            |:.:|::|||.......|...||.::.||| |:.|.|.|..||::....|.:||||.|  ..|..
  Rat   145 ILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEE--IYAPK 207

  Fly   248 VDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRG 312
            :......||.:..:.|::|.||.:|..|.|:|..||.:.:|.|.:....:  |:.|.:.:.:.
  Rat   208 LQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAV--KDIPKVLLPQY-- 268

  Fly   313 HAQAFISLA-----------AKEHKFAKFSASTI---AASSIAASMNGLKW 349
            ..:.||.:|           :.|.::...:|:.:   .:..:....:||:|
  Rat   269 SQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEW 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	43/141 (30%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	13/81 (16%)
Ccne2	NP_001102126.1	CYCLIN_SF	101..237	CDD:477360	43/139 (31%)
		CYCLIN_SF	241..329	CDD:477360	14/83 (17%)