Protein Alignment CycD and Ccne1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001094291.1
• Gene: Ccne1 / 25729
• RGDID: 2294
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 432
• Identity: 87/432 - (20%)
• Similarity: 152/432 - (35%)
• Gaps: 163/432 - (37%)

  Fly   113 EPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFL----KVEEKHHKIPDTYFSI 173
            :.|.....::|:.:.:.......|: ::|..||      |  :|:    |.|:...:.|.|.|..
  Rat    40 QDPDEEIAKIDKTVKSQDSSQPWDD-DSACVDP------C--SFIPTPNKEEDNELEYPKTAFQP 95

  Fly   174 QKDITPP-------------------------------------------MRKIVAEWMMEVCAE 195
            :| |.||                                           ||.::.:|:||||..
  Rat    96 RK-IRPPRASPLPVLNWGNREEVWRIMLNKEKTYLRDEHFLQRHPLLQARMRAVLLDWLMEVCEV 159

  Fly   196 ENCQEEVVLLALNYMDRFLSS-KSVRKTQLQILAAACLLLASKLRE---PSCRALSVDLLVVYTD 256
            .....|...||.::.||:::| :::.||.||::..:.|.:||||.|   |.....:     ..||
  Rat   160 YKLHRETFYLAQDFFDRYMASQQNIIKTLLQLIGISALFIASKLEEIYPPKLHQFA-----YVTD 219

  Fly   257 NSIYKDDLIKWELYVLSRLGWDLSSVTPLDFL-------------ELLMMRLPIGSKNFPDINIG 308
            .:...|:::..||.::..|.|.||.:|.:.:|             |:||.:.|
  Rat   220 GACSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTGEVLMPQYP------------ 272

  Fly   309 KVRGHAQAFISLA------AKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHFLLSLMTDL 367
                 .|.|:.:|      ..:....:|....:|||::        :|..|       |.||..:
  Rat   273 -----QQVFVQIAELLDLCVLDVGCLEFPYGVLAASAL--------YHFSS-------LELMQKV 317

  Fly   368 TSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPL 432
            :..:...:..|:..|           .||.:.|  :||.:...|.              .|.:|:
  Rat   318 SGYQWCDIEKCVKWM-----------VPFAMVI--REMGSSKLKH--------------FRGVPM 355

  Fly   433 PKAPAECVEQHQQQHNFGSAAPHRTHTCKMQA--QAQAQNEI 472
                       :..||.      :|||..:..  :|||:..|
  Rat   356 -----------EDSHNI------QTHTNSLDLLDKAQAKKAI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	43/184 (23%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	20/122 (16%)
Ccne1	NP_001094291.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		1/3 (33%)
		CYCLIN_SF	104..240	CDD:477360	30/140 (21%)
		CYCLIN_CCNE1_rpt2	244..357	CDD:410284	28/182 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..411		87/432 (20%)