Protein Alignment CycD and Ccnb1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_741988.1
• Gene: Ccnb1 / 25203
• RGDID: 2291
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 313
• Identity: 77/313 - (24%)
• Similarity: 129/313 - (41%)
• Gaps: 62/313 - (19%)

  Fly    84 EPPPPP-------PPP-----PPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTTTADPPATD 136
            ||.|.|       |.|     |.|.|..|........|:        ||...:.:...:|..|.|
  Rat    94 EPEPEPVMEVKHSPEPILVDTPSPSPMETSGCAPAEEYL--------CQAFSDVILAVSDVDADD 150

  Fly   137 NVNTAIGDPTLYSD--RCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQ 199
            .     |||.|.|:  :.:..:|:..|:...:...|. :.:::|..||.|:.:|:::|..:....
  Rat   151 G-----GDPNLCSEYVKDIYAYLRQLEEEQSVRPKYL-LGREVTGNMRAILIDWLIQVQMKFRLL 209

  Fly   200 EEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLRE--PSCRALSVDLLVVYTDNSIYKD 262
            :|.:.:.::.:|||:....|.|..||::....:.:|||..|  |.    .:......|:|:..|.
  Rat   210 QETMYMTVSIIDRFMQDSCVPKKMLQLVGVTAMFIASKYEEMYPP----EIGDFAFVTNNTYTKH 270

  Fly   263 DLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGK--VRGH--AQAFISLAAK 323
            .:.:.|:.:|..|.:.|....||.||..       .||      ||:  |..|  |:..:.|:..
  Rat   271 QIRQMEMKILRVLNFSLGRPLPLHFLRR-------ASK------IGEVDVEQHTLAKYLMELSML 322

  Fly   324 EHKFAKFSASTIAASSIAASM----NGLKW-----HLRSGHNLHFLLSLMTDL 367
            ::....|:.|.|||.:...::    || :|     |..| |....||.:|..|
  Rat   323 DYDMVHFAPSQIAAGAFCLALKILDNG-EWTPTLQHYLS-HTEESLLPVMQHL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	32/137 (23%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	27/98 (28%)
Ccnb1	NP_741988.1	Trypan_PARP	<59..>130	CDD:368653	10/35 (29%)
		CYCLIN_CCNB1_rpt1	157..285	CDD:410268	29/132 (22%)
		Interaction with CDK2. /evidence=ECO:0000250	159..167		0/7 (0%)
		Interaction with CDK2. /evidence=ECO:0000250	248..251		0/2 (0%)
		CYCLIN_SF	290..409	CDD:477360	27/99 (27%)