Protein Alignment CycD and Ccne1

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_031659.2
• Gene: Ccne1 / 12447
• MGIID: 88316
• Length: 408
• Species: Mus musculus
• Alignment Length: 489
• Identity: 90/489 - (18%)
• Similarity: 150/489 - (30%)
• Gaps: 193/489 - (39%)

  Fly    94 DDMERIE---YVAAFA---LATVSANHKR-----LSKPFNPL----LLETF-------------- 129
            |.:::|:   |...|:   |..:.|..:|     |::..||.    :|.||
Mouse    17 DQVKKIDKYLYAMRFSDETLRDIMARFRREMENGLARDTNPTATAKMLPTFVRSIPDGSEKGDFI 81

  Fly   130 --ELERNGVRFLAEQVSHHPP-----ISAVYAESDEFTVEGT-------VEPTLGFWMTKLLANP 180
              :|..:..|.|..:|||...     .|.:| |:.|..:.|:       |...||.:|.|
Mouse    82 ALDLGGSNFRILRVKVSHEKKQTVQMESQIY-ETPEDIIHGSRSRLFDHVAECLGDFMEK----- 140

  Fly   181 HAHLKLTFKK--TGETYSWSAPKCAIYNVIMGKMYMNFTSHMK----------------IESSGT 227
               .|:..||  .|.|:|:...:..:...::    :.:|...|                |:..|.
Mouse   141 ---QKIKDKKLPVGFTFSFPCSQSKLDEAVL----LTWTKRFKVNGVEGMDVVKLLNKAIKKRGD 198

  Fly   228 YDA--------------VFSFD--------------NKGYYNHKGGDVHVEGHIFEGKNKIKALY 264
            |:|              ...||              |..|.........|||.  ||:..|...:
Mouse   199 YEADIMAVVNDTVGTMMTCGFDDQRCEVGIIIGTGTNACYMEELRHMDMVEGD--EGRMCINTEW 261

  Fly   265 GNWTLFLASCDNEDFKHHRKEYLRMFNETVSEKDQGPVVPGSK---------------------- 307
            |      |..|:...:..|.|:.|       |.|:|.:.||.:
Mouse   262 G------AFGDDGTLEDIRTEFDR-------EIDRGSLNPGKQLFEKMVSGMYMGELVRLILVKM 313

  Fly   308 ----ILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDT--------VAPTD------------- 347
                :|:.....|:|.......|....::.:...|::..        |.|::
Mouse   314 AKEGLLFEGRITPELLTKGKIETKHVSAIEKSKEGLTKAKEILTRLGVEPSEDDCIAVQHVCAIV 378

  Fly   348 SRRRKDMKA---------LEDGKND---------EAEEFKHKYEEEQR----ERRTTKTGDVPMW 390
            |.|..::.|         |:|.||.         :...:|...:..:|    .||.....||...
Mouse   379 SFRSANLIAATLGAILTRLKDNKNTPRLRTTVGIDGSLYKMHPQYARRLHKTVRRLVPESDVRFL 443

  Fly   391 FAKNDEGH-------WAYKGGYWDRDYSNCLELF 417
            .:::..|.       |||:....:|..:..||.|
Mouse   444 LSESGSGKGAALVTAWAYRLADQERQIAETLEEF 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	37/191 (19%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	26/172 (15%)
Ccne1	NP_031659.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		2/9 (22%)
		CYCLIN_SF	101..237	CDD:477360	25/148 (17%)
		CYCLIN_CCNE1_rpt2	241..354	CDD:410284	22/127 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..408		7/28 (25%)