Protein Alignment CycD and Ccnd3

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_031658.1
• Gene: Ccnd3 / 12445
• MGIID: 88315
• Length: 292
• Species: Mus musculus
• Alignment Length: 319
• Identity: 112/319 - (35%)
• Similarity: 162/319 - (50%)
• Gaps: 56/319 - (17%)

  Fly   144 DPTLYSD-RCLENFLKVEEKHHKIP-DTYFS-IQKDITPPMRKIVAEWMMEVCAEENCQEEVVLL 205
            ||.|..| |.|::.|::||::  :| .:||. :||:|.|.|||::|.||:|||.|:.|:|:|..|
Mouse    18 DPRLLGDQRVLQSLLRLEERY--VPRASYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPL 80

  Fly   206 ALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELY 270
            |:||:||:||....||.|||:|...||||||||||.:  .|:::.|.:|||.::....|.:||:.
Mouse    81 AMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETT--PLTIEKLCIYTDQAVAPWQLREWEVL 143

  Fly   271 VLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTI 335
            ||.:|.|||::|...|||.|::.||     :.|......|:.|||.|::|.|.::.||.:..|.|
Mouse   144 VLGKLKWDLAAVIAHDFLALILHRL-----SLPSDRQALVKKHAQTFLALCATDYTFAMYPPSMI 203

  Fly   336 AASSIAASMNGLKWHLRSGHNLHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNI 400
            |..||.|::.||.....|...   |..|:..:|..|...:|.|...:|...:|..|
Mouse   204 ATGSIGAAVLGLGACSMSADE---LTELLAGITGTEVDCLRACQEQIEAALRESLR--------- 256

  Fly   401 DPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPHRTHT 459
                                  ......|.|:||||          ....|..|.:|.|
Mouse   257 ----------------------EAAQTAPSPVPKAP----------RGSSSQGPSQTST 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	64/136 (47%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	32/103 (31%)
Ccnd3	NP_031658.1	CYCLIN_SF	2..151	CDD:477360	64/136 (47%)
		CYCLIN_SF	156..260	CDD:477360	34/142 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..292		11/69 (16%)