Protein Alignment CycD and Ccnd2

DIOPT Version :10

• Sequence 1: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_036021678.1
• Gene: Ccnd2 / 12444
• MGIID: 88314
• Length: 349
• Species: Mus musculus
• Alignment Length: 294
• Identity: 114/294 - (38%)
• Similarity: 169/294 - (57%)
• Gaps: 25/294 - (8%)

  Fly   124 ERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPD-TYFS-IQKDITPPMRKIVA 186
            |.|....||     |..|:.|..|..||.|:|.|.:||::  :|. :||. :||||.|.||::||
Mouse    62 ELLCCEVDP-----VRRAVPDRNLLEDRVLQNLLTIEERY--LPQCSYFKCVQKDIQPYMRRMVA 119

  Fly   187 EWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLL 251
            .||:|||.|:.|:|||..||:||:||||:.....||.||:|.|.|:.|||||:|..  .|:.:.|
Mouse   120 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETI--PLTAEKL 182

  Fly   252 VVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQA 316
            .:|||||:...:|::|||.||.:|.|:|::|||.||:|.::.:||...:     .:..:|.|||.
Mouse   183 CIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKE-----KLSLIRKHAQT 242

  Fly   317 FISLAAKEHKFAKFSASTIAASSIAASMNGLKW----HLRSGHNLHFLLSLMT----DLTSVEQA 373
            ||:|.|.:.|||.:..|.||..|:.|::.||:.    :..:...|..||:.:|    |.....|.
Mouse   243 FIALCATDFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALTELLAKITHTDVDCLKACQE 307

  Fly   374 QVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMST 407
            |:...:|:....|::...|.....|. ||.:.:|
Mouse   308 QIEALLLNSLQQFRQEQHNAGSKSVE-DPDQATT 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	66/135 (49%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	33/111 (30%)
Ccnd2	XP_036021678.1	CYCLIN_CCND2_rpt1	61..209	CDD:410277	72/155 (46%)
		CYCLIN_CCND2_rpt2	214..318	CDD:410280	33/108 (31%)