DRSC/TRiP Functional Genomics Resources

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Protein Alignment CycD and Ccna1

DIOPT Version :10

Sequence 1:NP_523355.2 Gene:CycD / 32551 FlyBaseID:FBgn0010315 Length:477 Species:Drosophila melanogaster
Sequence 2:NP_031654.2 Gene:Ccna1 / 12427 MGIID:108042 Length:421 Species:Mus musculus


Alignment Length:323 Identity:89/323 - (27%)
Similarity:141/323 - (43%) Gaps:52/323 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 PTSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENFLKVEEKHHKIPDTYFSIQKDITP 179
            ||:|.|          ...|||..:..| :.|.|::. :..:|:..|..|:....|...|.|||.
Mouse   145 PTTHAQ----------SEEATDFGSDVI-NVTEYAEE-IHRYLREAEVRHRPKAHYMRKQPDITE 197

  Fly   180 PMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLRE--PS 242
            .||.|:.:|::||..|...:.|.:.||:|::|||||..||.:.:||::..|.:|||||..|  |.
Mouse   198 GMRAILVDWLVEVGEEYKLRTETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAILLASKYEEIYPP 262

  Fly   243 CRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINI 307
                .||..|..||::..|..|::.|..:|..|.:||:..|...||...:.|..:..:.   .|:
Mouse   263 ----DVDEFVYITDDTYTKRQLLRMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCIRT---ENL 320

  Fly   308 GKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHFLLSLMTDLTSVEQ 372
            .|.    .|.:||...: .|.|:..|.:||::...: |.:.       |.||....:...|....
Mouse   321 AKY----VAELSLLEAD-PFLKYLPSLVAAAAYCLA-NYIV-------NRHFWPETLAAFTGYSL 372

  Fly   373 AQVRDCM--LHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLP 433
            .::..|:  ||...:...|.           |::.....||....:|.|     :...|:.||
Mouse   373 NEIVPCLSELHKACLSIPHR-----------PQQAIREKYKASKYLHVS-----LMEPPVVLP 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CycDNP_523355.2 CYCLIN_SF 144..278 CDD:477360 48/135 (36%)
CYCLIN_CCND_rpt2 283..387 CDD:410220 22/105 (21%)
Ccna1NP_031654.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
Cyclin_N2 90..144 CDD:465146
CYCLIN_CCNA1_rpt1 132..294 CDD:410263 56/164 (34%)
CYCLIN_CCNA1_rpt2 298..420 CDD:410266 31/154 (20%)
Blue background indicates that the domain is not in the aligned region.

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