Protein Alignment tay and Fbrs

DIOPT Version :10

• Sequence 1: NP_573086.2
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_001419617.1
• Gene: Fbrs / 691899
• RGDID: 1594591
• Length: 981
• Species: Rattus norvegicus
• Alignment Length: 1044
• Identity: 236/1044 - (22%)
• Similarity: 330/1044 - (31%)
• Gaps: 404/1044 - (38%)

  Fly  1509 SPSTLSSSVIQKVISPKGESPCNKDRDSSYSTNIRSHGASTMLPGASQGIGLGSSFCG------- 1566
            |..:|.:..|....|...|...:.|.|.|::.:            .|:..|...:|.|
  Rat   212 SRHSLEAGYICDAESDLDERVSDDDLDPSFTVS------------TSKASGPHGTFNGNCEAKLS 264

  Fly  1567 IAPSQYGGTGTPVLSSSSSMPPGLGNLSSYSSKAALWLNSPANAVVTTCAPTTPIVSSGSARPTP 1631
            :.|...|      |..|...|||                 |...:|    |..|........|.|
  Rat   265 VVPKVSG------LERSQEQPPG-----------------PDPLLV----PFPPKDPPPPPAPRP 302

  Fly  1632 PLSNCTSMGIGMVNAASTARSSCNAISPLSIPATA-----------------GIHVSATNPSFQ- 1678
            |:|                       ||..:|||.                 |:..|....|..
  Rat   303 PVS-----------------------SPTPLPATPSLPPPPQHQLQLRVSPFGLRTSPYGSSLDL 344

  Fly  1679 --SSSYFPTPLAPPP--SSPSPATSSAAIISSSASQFNPAVSHSMSSIVTTAGATTTTASSVTQP 1739
              .||..|.|.||.|  :.|.|::||::..|||||..:..::|                    :|
  Rat   345 STGSSSRPPPKAPAPPVAQPPPSSSSSSSSSSSASSSSAQLTH--------------------RP 389

  Fly  1740 SVAAISNPVTN---TPH------PFSAESLFQPSKN----------------------DQADLLR 1773
            ...::..|:::   .||      |....||..|...                      .:.||:.
  Rat   390 PTPSLPLPLSSHSFPPHGLRPPPPPHHPSLVSPGPTLPPPPPLLQVPGHPGASAANALSEQDLIG 454

  Fly  1774 RELDSRFLDRS------GLAVTPTPPSSTYLRTDLQHQQ-HAHLHQH-----PQLLPP-----VS 1821
            ::|:||:|:..      |...:..|.:..:.:.:.|||. |.|.|||     |.||||     ..
  Rat   455 QDLNSRYLNAQGGPEVVGAGGSARPLAFQFHQHNHQHQHTHQHTHQHFTPYPPGLLPPHGHMFEK 519

  Fly  1822 APS--------TPLSAVQPSSGQIFP--PPLFKDISKISSVDPQFYRTGMGLPPGGYSGYTSAGL 1876
            .|.        .|..|..|:...:.|  ||.....|...:..|:  .|...|||  ..|...:||
  Rat   520 YPGKMEGLFRHNPYMAFPPAVPGLPPGLPPAVSFGSLQGAFQPK--NTNPELPP--RLGPVLSGL 580

  Fly  1877 LHSGLGGPTPFMPPNHLTSFAPKKTGRWNAMHVRIAWEIYYHQNKQSPEKQ---------PGFPT 1932
            ...|...|..|.||       .:|.|:|.|||||:|:.|..||.|...:..         |..|
  Rat   581 PQKGTQIPDHFRPP-------LRKPGKWCAMHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLP- 637

  Fly  1933 ASSNAGSINAPIPPGNMISGGGGGMASGASTPVNNVAAIPAVGGGVLVSNGPPSVLGMKTTPTLG 1997
                 |...| :|||..:           |.|.:...|..||
  Rat   638 -----GPYGA-LPPGQEL-----------SHPASLFTATGAV----------------------- 662

  Fly  1998 MSSTPQHILHRASEMPPSAAFPGGLPGRLAFETSPLAASFIGAPPSHIGTAVSPFGRYVTPFGFT 2062
                     |       :||.|        |.|:|.|.....:|.:||    .||||   |..|.
  Rat   663 ---------H-------AAANP--------FTTAPGAHGPFLSPSTHI----DPFGR---PTSFA 696

  Fly  2063 GLT-----HFGG----HLDSWRTNAMQRSVAYHPSSAAPSPNW----------PVKSDPGLDNAR 2108
            .|.     .|||    ..:|....|.:.|....|:.|:|...|          |....|. :.||
  Rat   697 SLAALSNGAFGGLGSPTFNSSAVFAQKESPGAPPAFASPPDPWGRLHRSPLAFPAWVRPP-ETAR 760

  Fly  2109 REAEERERELRDREQRERDRQRREREERERKEKEEKLKREQQERERERERDRKERERERREIERR 2173
            ....::||.:                    :.:|..:.:|:::|:....|
  Rat   761 TPGSDKERPM--------------------ERREPSVTKEEKDRDLPFSR--------------- 790

  Fly  2174 EMERERMLQQQRINESNKQAAVQAAAAATAPVRDRSPHRNVGELNTEIRIKEEHPRTKEEQDVML 2238
                    .|.|::.:..:|  :|......|.::            .:|:|||.   |||
  Rat   791 --------PQLRVSPATPKA--RAGEEGVRPAKE------------SVRVKEER---KEE----- 825

  Fly  2239 LRASAAAVGVGDPRYHSSSLAAAQASAAAAAAHHHHANFMAASRHGLPPPPSH--LTRTMMPPTL 2301
              |:|||         :::.|||.|:||||||        ||:..|  |...|  |.|...||.|
  Rat   826 --AAAAA---------AAAAAAAAAAAAAAAA--------AAATTG--PQGLHLLLERPRPPPFL 869

  Fly  2302 SVGGPITHFGAPAPPGWGIDPYRDPYPILRYNPIMEAALRHEAEERQKAINIYAAQSAAHLRSKE 2366
            ....|....|.|.|. |...|.|...|...|          ||.|.   :....|.:||.|.|.:
  Rat   870 GPSLPDRCAGFPEPT-WLAGPPRLARPPRFY----------EAGEE---LTGPGAMAAARLYSLD 920

  Fly  2367 PSPIPPSVGSLGPPPP-------HHRLQIVSSVAQSGVQQPGPPSQQQQQQMSSGGGMVKNSGGP 2424
            |:. |.....|.||||       .|.|......|..|...|..|:.             :.|..|
  Rat   921 PAH-PLLYSRLAPPPPPTATPGTPHLLSKTPPGALLGAPPPLVPAP-------------RPSSPP 971

  Fly  2425 QAPG 2428
            :|||
  Rat   972 RAPG 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_573086.2	Auts2	1900..>2023	CDD:464656	29/131 (22%)
Fbrs	NP_001419617.1	Auts2	597..797	CDD:464656	65/315 (21%)