Protein Alignment tay and Fbrsl1

DIOPT Version :10

• Sequence 1: NP_573086.2
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: NP_001136114.1
• Gene: Fbrsl1 / 381668
• MGIID: 1920907
• Length: 1031
• Species: Mus musculus
• Alignment Length: 1221
• Identity: 278/1221 - (22%)
• Similarity: 409/1221 - (33%)
• Gaps: 361/1221 - (29%)

  Fly  1310 RSSDSRNSR-ESPAS-LKSTPS----NIGLNVS--MAPT-LRSITPLNNSSAISSGASQPVVSVV 1365
            |...:|::| :||:| .:..||    |.||:.:  ..|| ||:..|.......||...:.|:.
Mouse    20 RREAARDARAQSPSSGEEPEPSPGKENAGLHGAPPQRPTPLRAARPPRRRRRESSSQEEEVID-- 82

  Fly  1366 PSANSTALSMSNPHISHSHHVPAYASGAFSSSAAAGTSTPNSGLSTLAVTSLSTSAAPQPHSHFP 1430
                                  .:|..:||:                 :.:|....|.:||....
Mouse    83 ----------------------GFAIASFST-----------------LEALEKDMALKPHERKE 108

  Fly  1431 QSTQMLPQSGNFSSVSHLLTTHPMSSQNQPMVRCGSTLYSQS-------SAAATAPPSAAAAVSN 1488
            :..|.|.:.             |..|:|     |.|...|::       |....|.||.......
Mouse   109 KWDQRLVKK-------------PRESEN-----CPSAELSENRQPLEVGSPGQDAEPSCDEGTRK 155

  Fly  1489 --FTPSVLAVQSLTTAVTSSSSSPSTLSSSVIQKVISPK--GESPCNKDRDSSYSTNIRSHGAST 1549
              ..||.....::......:|...|.|.:|..|:..|.:  .:|.........||.:..|
Mouse   156 VPLQPSKQMKVTMARGGDRNSDDDSVLEASSSQRSSSREQLSDSSAQAVSGRGYSCDSES----- 215

  Fly  1550 MLPGASQGIGLGS-SFCGIAPSQYGGTGTPVLSSSSSMP--PGLGNLSSYSSKAALWLNSPANAV 1611
               |......:|| .....||.:..|.|....:.:.::|  .||...|..|::|.|...:||.:.
Mouse   216 ---GVDDKASVGSEKLFAPAPDKGSGRGEKSEAKAGAVPKVSGLERSSELSTEAFLPATAPAPSG 277

  Fly  1612 VTTCAPTTPIVSSGSARPTPPLSNCTSMGIGMVNAASTARSSCNAISPLSIPATAG--------- 1667
            .....|.:|:|.    |..|.:.:    .:.........|.|.....|||:.|..|
Mouse   278 PAPGTPASPLVK----REAPVVPH----HVPQPQLTPQHRGSLPTHVPLSLGAFVGPGPGPGQVA 334

  Fly  1668 ---IHVSATNPSFQSSSYFPTPLAP----PPSSPSPATSSAAIISSSASQFNPAVSHSMSSIVTT 1725
               :|:.:.:.|..:.|..|..||.    .|..|.|..|::.:...|.:|.....:...::..|.
Mouse   335 SSSLHLHSLSRSSSTVSGTPLGLAKHVTLSPHGPGPHLSTSHLALRSQAQHQHHAAAMFAAPPTL 399

  Fly  1726 AGATTTTASSVTQPSVAAISNPVTNTPHPFSAESLF---------QPSKNDQAD--LLRRELDSR 1779
            .......|||:..|.            ||..|..|.         ||......|  |||:||::|
Mouse   400 PPPPALPASSLVIPG------------HPADASLLISFNQPIMYCQPHSGILIDHELLRQELNTR 452

  Fly  1780 FL----DRSGLAVTPTPPSSTYLRTDLQHQQHAHLHQHPQ-----LLPPVSAPSTPL-SAVQPSS 1834
            ||    :|.|.::.|    ...||.:.....|.|.|||..     ..|....|.||| ....||.
Mouse   453 FLVQNAERPGASLGP----GALLRAEFHQHTHQHTHQHTHQHQHTFAPFAGLPPTPLMPPTAPSP 513

  Fly  1835 GQIFPP----PLFKDISKISSVDPQFYRTGMGLPPGGYSGYTSAGLLHSGL----GGPTPFMPPN 1891
            ...|.|    |.|:..:..:|::              .:|.:||  :|:.|    |...|:..
Mouse   514 FDKFSPKLDSPYFRHSNTSNSIE--------------ITGRSSA--VHTFLQKAPGVSDPYRT-- 560

  Fly  1892 HLTSFAPKKTGRWNAMHVRIAWEIYYHQNKQSPEKQPGFPTASSNAGSINAPIPPGNMISGGGGG 1956
                 |.:|.|:|.|:||:|||:||:.|.|...:..|......:.....:.|..|         |
Mouse   561 -----AVRKPGKWCAVHVQIAWQIYHQQQKMKMQLDPHKLEVGTKLDLFSRPPAP---------G 611

  Fly  1957 MASGASTPVNNVAAIPAVGGGVLVSNGPPSVLGMKTTPTLGMSSTPQHILHRASEMPPSAAFPGG 2021
            |.||...|.:  .|.|     :..|.|       .|.||             |:...|||.....
Mouse   612 MFSGFHYPQD--LARP-----LFSSTG-------ATHPT-------------ANPFGPSAHHGSF 649

  Fly  2022 LP-GRLAFETSPLAASF----IGAPPSH----IGT-AVSPFGRYVTPFGFTGLTHFGGHLDSWRT 2076
            || |.|   |.|.:.|.    :|:..:|    :|: |::|......|...|.|.......|:|
Mouse   650 LPTGHL---TDPFSRSSTFGGLGSLSNHAFGGLGSHALTPGSSIFAPKEGTALLGLPSPHDAW-- 709

  Fly  2077 NAMQRSVAYHPSSAAPSPNWPVKSDPGLDNARREAEERERELRDREQRERDRQRREREERERKEK 2141
            |.:.|   ..||...|.| ||...|          .||...|.:.: ||.|: .:|..||:..||
Mouse   710 NRLHR---VPPSFPTPPP-WPKPVD----------TERLSALTNHD-REPDK-GQEEHERDLLEK 758

  Fly  2142 EEKLKR---------------EQQERERERERDRKERERERREIERREMERERMLQQQRINESNK 2191
            ...|..               ::...|..|.....|||.|.|..|.....:|         :..|
Mouse   759 TRLLSHGSPVAPVGHPISSLLQRGSGELSRPGVLTEREAETRVKESHSPSKE---------DGAK 814

  Fly  2192 QAAVQAAAAATAPVRD--------------RSPHRNVGELNTEIRIKEEHPRTKEEQDV--MLLR 2240
            .||...:....|.:.|              ::|.|..|    ::::|||. |..|..|:  :.:.
Mouse   815 LAARPPSPYCKAALGDCLRLAGLLGRESGKQTPDRPQG----DVKVKEER-REDETPDLTGVSVH 874

  Fly  2241 ASAAAVGVGDPRYHSSSLAAAQASAAAAAAHHHHANFMAASRHGLPPPPSHLTRTMMPPTLSVGG 2305
            ::|..:|:|.                        |.|:.       .||....|.:..|..|
Mouse   875 STATHMGLGT------------------------AGFVW-------DPPRDTYRGLELPRRS--- 905

  Fly  2306 PITHFGAPAPPGWGIDP-------YRDPYPILRYNPIMEAALRHEAEERQKAINIYAAQ--SAAH 2361
                |.|| ||..|..|       |||..| ..|:|.....:|.|..||.:..:..||.  .|.|
Mouse   906 ----FPAP-PPAAGPSPFELSERAYRDREP-HDYSPERLQEVRREELERARVPDSDAAALLPAVH 964

  Fly  2362 LRSKEPSPI--------PPSVGSLGPPPPHHRLQIVSSVAQSGVQQPGPPS 2404
            .....|..:        ||:...||.|||        .|...||  |.||:
Mouse   965 YPRLAPGALHGALLARTPPAAAVLGAPPP--------LVTAGGV--PTPPA 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_573086.2	Auts2	1900..>2023	CDD:464656	32/122 (26%)
Fbrsl1	NP_001136114.1	Auts2	564..767	CDD:464656	70/259 (27%)