Protein Alignment tay and auts2b

DIOPT Version :10

• Sequence 1: NP_573086.2
• Gene: tay / 32547
• FlyBaseID: FBgn0260938
• Length: 2486
• Species: Drosophila melanogaster
• Sequence 2: XP_001921311.2
• Gene: auts2b / 100150849
• ZFINID: ZDB-GENE-131127-20
• Length: 748
• Species: Danio rerio
• Alignment Length: 757
• Identity: 185/757 - (24%)
• Similarity: 276/757 - (36%)
• Gaps: 229/757 - (30%)

  Fly  1731 TTASSVTQPSVAAISNPVTNTPH--PFSAESLFQPSKNDQADLLRRELDSRFL-----DRSGLAV 1788
            |||.....|.:...:.||.:||.  |::           ..||||:||:||||     ||.|...
Zfish     5 TTALPPPPPLLTGSALPVPSTPSAGPYT-----------DHDLLRQELNSRFLASQTADRGGALA 58

  Fly  1789 TPTPPSSTYLRTDLQHQQHAHLHQHPQLLPP-----VSAPSTPLSAVQPSSGQIFPPPLFKDISK 1848
            .|     .||||:....||.|.|.|.....|     :.:|:.||  |:..:.|....|...|..:
Zfish    59 PP-----AYLRTEFHQHQHTHQHTHQHTFTPFPHSIMPSPAAPL--VRTPARQFEKYPAKVDSFQ 116

  Fly  1849 ISSVDPQFYRTGMGLPP-----GGYSGYTSAGLLHSGLGGPTPF------MPPNHLTSFA----- 1897
            ..|:.|.:.....|:||     |.:|  :..|........|...      :|..||...:
Zfish   117 RHSLVPSYPSVMTGIPPMVPPAGPFS--SLQGAFQPKASNPLDVVSRPGSVPHQHLQKDSRLLDP 179

  Fly  1898 ---PKKTGRWNAMHVRIAWEIYYHQNKQSPEKQ-----------PGFPTASSNAGSI-----NAP 1943
               |||.|:|.||||.|||::|:||.|...:.|           |.|...||.:..:     :.|
Zfish   180 MCKPKKPGKWCAMHVHIAWQVYHHQQKIKKQMQIEPHKLEFGFKPEFLNQSSGSNFVGLQPRDLP 244

  Fly  1944 IPPGNMISGGGGGMASGASTPVNNVAAIPAVGGGVLVSNGP--PSVL---GMKTTPT-LGMSSTP 2002
            .|                ||.::|.              ||  |||.   .::.||: |.....|
Zfish   245 RP----------------STILSNA--------------GPTHPSVSPYGSLQHTPSNLQSGLVP 279

  Fly  2003 QHILHRASEMPPSAAFPGGLPGRLAFETSPLAASFIGAPPSHIGT-AVSPFGRYVTPFGFTGLTH 2066
            .|      |....|...|||        :.|::|..|.    :|. :::|.....|..|....|.
Zfish   280 HH------ESLNKAVTFGGL--------TTLSSSAFGG----LGNPSLTPNAANGTKDGKMAATS 326

  Fly  2067 FGGHLDSWRTNAMQRSVAYHPSSAAPSPNWPVKSDPGLDNARREAEERERELRDREQRERD---- 2127
             .|.|:.|  |.:.::    |||....|..|..|:|          ||...:.||...:||
Zfish   327 -NGTLEPW--NRLHQT----PSSFPTPPLCPRPSEP----------ERAPSVPDRVANKRDSVDN 374

  Fly  2128 RQRREREER----------------ERKEKEEKLKR----EQQERERERER---------DRKER 2163
            :|.:||..:                |.|:..|.||.    |.:|.||.||:         :|:..
Zfish   375 KQDQERGLKDKSNVRQLSPVRNITLENKQSTESLKASTPDEHKEEERAREKPPAQELLHQNREIE 439

  Fly  2164 ERERREIERREMERERMLQQQRINESNKQAA------------------VQAAAAATAPVR-DRS 2209
            |::.:||...:.|::...:||:..| :|.||                  :|....|...:| :..
Zfish   440 EQKHKEIHSDKKEKDVKTEQQQPAE-DKPAAKESSSPKQREDLKRPNTDIQPWEPAEKKIRGEFE 503

  Fly  2210 PHRNVGELNTEIRIKEEHPRTKEEQDVM--LLRASAAAVGVGDPRYHSSSLAAAQASAAAAAAHH 2272
            ||..    .:::|:|||. |..::.||.  |........|...|..:.|||:.........|.|
Zfish   504 PHAK----TSKVRVKEER-RDDQDHDVTSHLKVLEKTWQGPRTPATNCSSLSTLPLPIGIPAGH- 562

  Fly  2273 HHANFMAASRHGLPPPPSHLTRTMMPPTLSVGG-PITHFGAPAPPGW--------GID-PYRDPY 2327
                            |......::.|.|.||. |:......:|..|        |:| |.||..
Zfish   563 ----------------PGLDRSRLVSPFLGVGPLPVAERLPYSPQHWESMRNVYRGLDLPRRDLL 611

  Fly  2328 P---ILRYNPIMEAALRHEAEERQKAINIYAAQSAAHLRSKE 2366
            .   ::|.:|:..|.:.|.|..|:..:...|.:...||..::
Zfish   612 GKDLLMRADPLQRAIIGHPAYPREPFLQSMALEQRNHLEERQ 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tay	NP_573086.2	Auts2	1900..>2023	CDD:464656	38/144 (26%)
auts2b	XP_001921311.2	Auts2	185..386	CDD:464656	67/265 (25%)
		PTZ00121	<368..516	CDD:173412	34/152 (22%)