Protein Alignment ArgRS and mrs1

DIOPT Version :10

• Sequence 1: NP_573081.1
• Gene: ArgRS / 32539
• FlyBaseID: FBgn0027093
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_596077.1
• Gene: mrs1 / 2540548
• PomBaseID: SPBC25B2.09C
• Length: 618
• Species: Schizosaccharomyces pombe
• Alignment Length: 636
• Identity: 169/636 - (26%)
• Similarity: 278/636 - (43%)
• Gaps: 108/636 - (16%)

  Fly    86 VFRQAIASAFPEFRDTPV-IIAPVNSTSAKFGDYQCN------NAMGLSKKLKEKGINKAPRDIA 143
            |:|..|:|...:.....| :|.|...||........|      ...|..::|.:|.....|:|:
pombe    35 VYRSYISSELSKINGVDVSLIYPALETSISKDSADLNLPVPRLRVKGKPQELAQKWAEAFPKDL- 98

  Fly   144 TELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEVIKKR----------- 197
                           :|:...|   :||..::...:|:.|:.     |.:.::|
pombe    99 ---------------VEVTANG---IFLRFNFNGPSLTKLIL-----PIIWEQRENYGRNESGSG 140

  Fly   198 --VLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHL---- 256
              .:::||||||||..|.|||||||||..|..|.|.....|.|:|:|||||.|||:|....
pombe   141 KVAVIEFSSPNIAKPFHAGHLRSTIIGSFLANLHESQGWKVHRVNYLGDWGKQFGLLAIGYKKYG 205

  Fly   257 -EDRFPNYLNESPPISDL-QLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVP------------- 306
             ||:.     :|.||..| .::.|.:....:|||:.:|   .:..:..||:|
pombe   206 DEDQL-----KSNPIRHLYDVYVKVNADATEEDEKIQK---DKAEAESKGLPYTPPLSLHDKARE 262

  Fly   307 ----------NSIKAWELICNVSRKEFQTIYERLDISVKE-RGESFYQSRMLS-VVEYLRGKGLL 359
                      .|:|.|....::|..:.:..|:||:|...| .|||.....::: :|:.||...|:
pombe   263 FFKRMEDGDEESLKVWARFRDLSITKLKDTYDRLNIHYDEYDGESQVSLELMNKMVDELRSLNLI 327

  Fly   360 EVDEGREI--MWPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHF 422
            |.|.|..:  :...|.|.|..: :.|.||...|.|.|:.....|.|:...|..||||.|.|..:|
pombe   328 EEDGGALLIDLSKHDKKLGKAI-VQKRDGTTLYLTRDIGTAYKRYEKYKFDKSIYVVSSQQDMYF 391

  Fly   423 NTIFKAAERSAILNPLSHRVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLD---EGMKRSLQQLE 484
            :.:||..|....  ..:.:..|:.:|:|.|     ..||.|..|.|.|:::   |.|.:.:|:.|
pombe   392 SQLFKIFELMGF--DWAKKCVHINYGLVQG-----MSTRKGKAVFLDDIMEVAKEEMHKVMQKNE 449

  Fly   485 SRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICS 549
            .: ..:|..|:|:.|.....|   |:..|....||::|.|.:.:|....|:|..||.|.::|:.|
pombe   450 EK-YAQVENPEEVADIVGKTA---IRIQDSTGKRINNYAFDWSRMTSFEGDTGPYLQYAHSRLSS 510

  Fly   550 IARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVF 614
            :.||  .::|: .||:.....:|.....:.|.:.|.:..|:|....:......:..:.|::....
pombe   511 VRRN--VNYTD-EEIMGANLELLTEPDAYDLVRLLGQYPDVLKNAFRFQETSTVVTYLFKLTHAV 572

  Fly   615 TEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM 665
            ::.||..:.  :.::.||   ..:|:.|..|...||.....:|||.|:.:|
pombe   573 SKLYDILWV--RGRERDI---QLARLALFGAAKQVLNNGMTLLGLTPLERM 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	PLN02286	83..665	CDD:215160	168/634 (26%)
mrs1	NP_596077.1	Arg_tRNA_synt_N	34..112	CDD:214975	19/95 (20%)
		ArgS	78..618	CDD:439789	158/591 (27%)