Protein Alignment Rhp and Brox

DIOPT Version :10

• Sequence 1: NP_511168.3
• Gene: Rhp / 32531
• FlyBaseID: FBgn0026374
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_001020840.1
• Gene: Brox / 305031
• RGDID: 1307161
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 70/333 - (21%)
• Similarity: 130/333 - (39%)
• Gaps: 96/333 - (28%)

  Fly   154 YIDAIADMTDTRQASKTPSRDALGVALLFRYYNTLYYVERRFFPPDRNLGVYFEWYDSLTG-VPS 217
            :|:::.|.|   |.||                  |.|::.            |:|.|:|.| |||
  Rat    71 FINSVGDST---QESK------------------LRYIQN------------FKWTDTLQGHVPS 102

  Fly   218 CQRTIAFEKACTLFNLGGIYTQIGAR---HDRTTERGLDLAVDSFLRAAGVFRHIYDTFTNAPSM 279
            .|:...||.....||:...||:..:|   .:..||........|...|||:|:|:.:  ::.|.:
  Rat   103 AQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKE--SHIPKL 165

  Fly   280 --------DLKPQVLDVLVSLMLSQARECLFEK-LQLQ-----IEAMSHDCQAFRDLAGEAAQIS 330
                    ||:.:::|..:....::|:|....: ::|:     |.|::::..:|...|      .
  Rat   166 LTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYETASFYQKA------D 224

  Fly   331 HEYNEMHKNIQANDTHTYLPECWAGLVPVKAELYKAFAHFYKARSIDATDEL-KASKSSQKNQES 394
            |..:.:.....|.         |...:.:|...|.|:|:.|..:::.|:|:. :|.:|.|:.::.
  Rat   225 HTLSSLEPAHSAK---------WRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKL 280

  Fly   395 FIGNSQEVERITTADYGASDEASTSIANKLAHLKEALASIEEAQRLQRMCRFLKNKASLTEVMKE 459
            :    .|.|.: ..:||.: :.....|....||                  |.:...||   :|.
  Rat   281 Y----AEAEAL-CKEYGET-KGPGPTAKPSGHL------------------FFRKLGSL---VKN 318

  Fly   460 VHSKSQEE 467
            ...|.|.|
  Rat   319 TLDKCQRE 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhp	NP_511168.3	HR1_Rhophilin-1	34..118	CDD:212023
		BRO1_Rhophilin	122..514	CDD:185767	70/333 (21%)
		PDZ_canonical	578..642	CDD:483948
Brox	NP_001020840.1	BRO1_Brox_like	4..356	CDD:185766	70/333 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	376..411