DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rhp and brox

DIOPT Version :9

Sequence 1:	NP_511168.3	Gene:	Rhp / 32531	FlyBaseID:	FBgn0026374	Length:	718	Species:	Drosophila melanogaster
Sequence 2:	NP_001096412.1	Gene:	brox / 100125017	XenbaseID:	XB-GENE-5745545	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	71/316 - (22%)
Similarity:	125/316 - (39%)	Gaps:	59/316 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 LKETKEINFMEPFSDFILEH--YSEEPSMYIDAIADMTDTRQASKTPSRDALGVALLFRYYNTLY 189
            |:.|: ...:|.|||....|  .......|...:....|:....   ::|           |.|.
Frog    36 LRSTR-ARLLELFSDITCNHEMMKNATDAYFSLLLGFIDSLDGG---TQD-----------NKLR 85

  Fly   190 YVERRFFPPDRNLGVYFEWYDSLTG-VPSCQRTIAFEKACTLFNLGGIYTQIGAR----HDRTTE 249
            |::.            |:|.|:|.| .||.|:...||.....||:...||:..:|    .|.|.|
Frog    86 YIQN------------FKWTDTLQGNAPSAQQDAVFELVSMGFNVALWYTKYASRLAGKEDITEE 138

  Fly   250 RGLDLAVDSFLRAAGVFRHIYDTFTNAPSM--------DLKPQVLDVLVSLMLSQARECLFEKLQ 306
            ...::. .|...|||||:|:.:  .:.|.:        ||:.:|:|.......::|:|....:
Frog   139 EAKEVH-RSLKIAAGVFKHLKE--NHIPKLITPVEKGRDLETRVIDAYTVQCQAEAQEVTIAR-- 198

  Fly   307 LQIEAMSHDCQAFRDLAGEAAQISHEYNEMHKNIQANDTHTYLPECWAGLVPVKAELYKAFAHFY 371
             .|| :.|:......||.|.|   :.|.::...:...|. .|:.: |.....:|...|.|:::.|
Frog   199 -AIE-LKHNPGLIAALAYETA---NYYQKVDHTLATLDP-VYIAK-WRSYTQLKMCFYMAYSYCY 256

  Fly   372 KARSIDATDELKASKSSQKNQESFIGNSQEVERITTADYGASDEASTSIANKLAHL 427
            ..:::.:.|:...:..|.:..|.|.|.::.:    ..:||.:....|: |....||
Frog   257 HGQTLLSADKCGEAIRSLQEAEKFYGKAEAL----CKEYGETKGPGTT-AKPSGHL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rhp	NP_511168.3	HR1_Rhophilin-1	34..118	CDD:212023
		BRO1_Rhophilin	122..514	CDD:185767	71/316 (22%)
		PDZ_signaling	570..642	CDD:238492
brox	NP_001096412.1	BRO1_Brox_like	4..356	CDD:185766	71/316 (22%)
brox	NP_001096412.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910