|
Fly 9 KKGSSELTAECRELIDELTKRRTRAELLEFLDTVHVWIYGKCELYHWIEILDRFD-KILEEASRH 72
|....:|.|..:.|:|.|....| ...||.::.:..|...:.:||.||.||||.| .:|:.|.::
Yeast 9 KARKEKLAAGYKPLVDYLIDCDT-PTFLERIEAIQEWDRSRDDLYVWIPILDRMDGLLLKVAEKY 72
Fly 73 VNGNEFVLQCDTNFQET---DVTLLLHVLNFTTLLIEHSFSRHLYNSIEHLTVLLSSQNMDIVLA 134
....:...:|:....|. ||...|.:|.||..|:.::.:|.:|:|.:.|..||:..|..|.||
Yeast 73 KYKQDPKKECEVKLVEMEAHDVDYCLKMLKFTRRLLLNTENRFVYSSGDVLMYLLNCPNFTIKLA 137
Fly 135 VLNLLYMFSKRSNFIPRLPFEKKELLIVKLFNIAERWGDPNYGLSLKDCCIGEPKLEFLYQLCID 199
|:.:|.:..:| |: ..:::::...:| ||.| :.:..|:....|...
Yeast 138 VMRILAILGER--FV----IAREKIVAHNIF------GDHN---------LRKKTLKLALSLSSS 181
Fly 200 YVDEHGHAAQLEIPDMMDLCHTASAPEVIKTIAGQISKPSEAIKMRIAHRVRLISGFNNYKLRLQ 264
.:||.| |...::||..... ..|.:..|:|..|... |::|...|
Yeast 182 VMDEDG-----EHFSLVDLYFDKK------------KVPQKWRKLRFTHYTS-----NDFKKSSQ 224
Fly 265 FVQARLQAVSILIYSNALQDNTDKVLYAGFGEELCE------------LIDKEDVHLVEIRAAVL 317
|..:| |..|.:..||... .:|||| |:..|......|:|:|.
Yeast 225 ------QKNNI----NETQTSIKKVTMT--TQELCEHSLQQIFDKGMALLPAESWFDFSIKASVA 277
Fly 318 RTLTSMLHFDRNPNV-----------------------PRAGSRLMKIVHY-------------T 346
:..:. |...|: |:..|:|.::..| |
Yeast 278 KAFSD----DSGENIDLRNIIIETKLNAIAFVNTIFSPPQVSSKLFELDPYAFNSLTDLISLSET 338
Fly 347 GAERQGGTLPLLVRDCID-----------NL---TTHGLTERYPLILATSLFSLLYHLASYEMGG 397
...::..|..|...:||. || .:||| ||.:|.::|......
Yeast 339 KIPKELRTDALFTLECISLKHVWCSDIIRNLGGNISHGL-----------LFQILRYIAKTLREA 392
Fly 398 TALVKSGMMQSLLCVISWPGVDLEHITFVTRAVRVIDLITNI-DIARFHQNNGLNVFIDRLEK-- 459
| ..:|.|: .||...||:|: |:...|::......|..|.:
Yeast 393 T-----------------DEIDEEY------NVRFFYLISNLADVKPLHESLFAAGLIPTLLEIV 434
Fly 460 EIKSCCKALADIGITLKESTLRDDHKLDTSLDHVDEDVE--DGSGENASVTSGNASPRRDNSSDG 522
.|::| ..|.:.....|.|:|.:|:.:...| :..|....:||
Yeast 435 SIRNC---------PYKRTLASATHLLETFIDNSETTTEFIENDGFTMLITS------------- 477
Fly 523 ATGAGSIVYRAYHEHIGGAGSGAGLLDIGGARSSLSGGSSGTSGMGAGSINRDGSAARPP--AIM 585
.|..|.:...|. ...:|| :::
Yeast 478 --VANEIDFTLAHP----------------------------------------ETWQPPKYSVV 500
Fly 586 YPTNSYYARPLAERKAELSSQLPSSLAPKKPSCVTQRAALLKSMLNFLKKSIQDHAHFSNMRNIM 650
|.:.|: |.||..: :|||.:|..|.....| .:||::
Yeast 501 YYSISF--RELAYIR-----------------------SLLKLVLKLLSTDSGD-----RIRNLI 535
Fly 651 ETSLTQSLRHIIANAEYYGPSLFLLATDVVTVYVFNEPSLLSSLQDLGITSVMLKALLQKDVPAT 715
::.:..||:.|:.|...:|.:|.....|||...:.:||::...|.:.|:...::.. ..|.:..:
Yeast 536 DSPILVSLKKILENKLVFGLTLITYTLDVVQKVINSEPTIYPVLVEAGLIPYVIDN-FPKLIGPS 599
Fly 716 REVLGSLPNVFSALCLNERGLFEFLSYDPFDKVLKVLLSPDYLVAMRRRRSSDPLGDTATNLGNA 780
.|:|..||:|.||:|||..||.:.......:.:...||..|:...:.. ||.:|..|..
Yeast 600 AELLSLLPDVVSAICLNPEGLKQVKEKGLINNLFDFLLDADHARILTG-------GDRSTEYGTD 657
Fly 781 MDDLIKHHPYLRADATEAIVRLL--------NE---LVRLGSDPSFICWRANKESSGSGSGSGSH 834
:|:|.:|:|.|:|:..||:..:: || |.....|..:...|.|:|.. :....|
Yeast 658 IDELARHYPDLKANIVEALCNVIRKMPSTFRNEREFLFTSPKDQKYFFHRKNEEIL---TDKEEH 719
Fly 835 GGGHHVASTPSPMVMVAGTGSASSVLQGAADTNDSSGDDDDDDDEMSSASQQQQQPTTPGQGGGP 899
...:........|: .:.:|||.|.:
Yeast 720 EPAYWELLDKGTML-----DTFTSVLFGMS----------------------------------- 744
Fly 900 STPRTQQAGGVVGSGAGATGTPAAASQAVKVVTPPEREAIPLIDYILNVMKFIEAIFSNSPNGDH 964
:|:|: ||..|....
Yeast 745 -----------LGNGS----------------------------------------FSQVPQHLE 758
Fly 965 CREFVLHGGLKPILQLLSLPNLPVDSPVSTTSQAVANVCKAILSQAQETKVLDVA----LKQLAD 1025
.|:| |.::.:.|.|.: ..||.|::||.:.: |..:.|..|.| :|.|.|
Yeast 759 ARDF---------LAIIFMENPPYE---YFTSVAISNVTEVL--QYLDEKYEDYAFMDVMKVLND 809
Fly 1026 IVAQLKPLIKHFTFPGGSVLLAELVCCQRLEDGFANAEYTPILHNMSFVHGYVVML---VHLCRN 1087
||:.|......|.......| .|| .:::...|..:..| :::..|
Yeast 810 ---QLENLNDFLNSPNDRSFFLE-------RDG---------ENSVRSCHSKLCRLAAILNIVTN 855
Fly 1088 ASNDMRTILLKRWGVNRETGVQLLQQLVQLY-------ISLVWESTILLNLCSDEP---TQH-PD 1141
...|:.|:..|| ::|:| .||:....:|...|:.|. .|| ||
Yeast 856 VYIDLTTLSCKR--------------IMQIYSYFDKRGFSLIKNLKLLFQKCALEEMYIRQHMPD 906
Fly 1142 -LIWDEIAAQMSAAAGTADPL----TEAELSRKLERAAEFRTKYTPEEQFRYIKSLLAASSRLGR 1201
:|.:.:...:...:|...|| .:.:...:..:....:|:.| .|.|.|...|.:::
Yeast 907 SVITETMPLPIVDVSGDGPPLQIYIDDPKKGDQKGKITSVKTRNT--LQMRTILYTLQSNT---- 965
Fly 1202 ALAELLGTLVKLSVGSPQTRQRR--------INDLISNITKVPTPEAREIARILSSILV--NGFS 1256
|.|....::||.......:.: ..:::.|: :...:|.|:...|..||| |..:
Yeast 966 --AILFRCFLRLSHSRNMDLEHKDLTTEVHIFENVVENV--IEMLKATELEGHLPYILVLLNFNT 1026
Fly 1257 HESILPKPVPK----LKL--TFLICSVGFTGPMLFDDKRSAFHLMISQFCAENGLKAFFEMFYWA 1315
....:||..|. |:. .::....| |.:|: .|::...|.....:|..
Yeast 1027 FVFTIPKASPNSTEILQTIPAYIFYQKG--GYLLY------LHIIRDLFTRMTKIKDL------- 1076
Fly 1316 LSLDNVSQKFEFDQWASMEDLMQSHEDDKRDCPEGTGEFLDAWLQLLEKMVNPRAM------LDS 1374
.||||::...|.:...::..|:.:. .|.:..:| .|.|.|.::: :|.
Yeast 1077 SSLDNINYIDESNGILTLSCLINAL------------TFYNKSMQ-TETMENVQSIGKYYVSIDD 1128
Fly 1375 PYTMSPRLNYMPDSVPFEPVFYLIHIHQLAM-------QALRRIWARRPIPNYGPSMFETMILIL 1432
.|.:...| :|| |.:..||| .:|.:..:| |...|:|:.::.:|
Yeast 1129 DYNIMKAL-----TVP-------IKVMALAMILDLDKSDSLFKTQSR----NVPYSVFKQLLSML 1177
Fly 1433 KHLIKSHQTLLDRYHTRMKEIKFENLYIRSTDDGLNADHIKTLTDMGFMHYHVIEALRTNASLEE 1497
|:: |.|:.| :.|.|.: :|:.:|.......||.|
Yeast 1178 KNI-------------------FTNVNI----------YTKELYE---LHWDLIFPPIKKISLFE 1210
Fly 1498 ATDYLLNNPEASSLSTTGGQSSSSAPPPPPPPSASTMDIDVDVPADGESTQSKSSTSPNSSYDYK 1562
... :..:..|:.|:.||. |:||| .|....||.....||
Yeast 1211 QVG-IPGDVAANYLTDTGD----------------------DLPAD----NSIGLFSPEQWEKYK 1248
Fly 1563 HL-----------------------KLMPSLIFDRFCDEAISRAFEFMEAIPDTVNSAADLIAVL 1604
.| |.:..|....|.|...||.|..:...|..||:.|..:..:
Yeast 1249 KLIGEDKSIYYPQPMQAQYYKGCSSKELDELRDTFFNDGLPSRIFTVLPFYPKLVNAFAKTLLQI 1313
Fly 1605 YRRHNHLNKQVFVTNFVRNIIQWVDFTLQLFEPAKTTGSKASRLEECLTGMTATRLFVRLKTSTL 1669
:.:::. ..:||....:..|:: ..|.:|| |..:...|| .:
Yeast 1314 FTKYDE-PTEVFAGRILDRILE-----TDLDDPA--------------TLSSLIHLF------GI 1352
Fly 1670 LLEENY-----SDLHRPLVEAITAQDAMVSLVKLLDCMSQWMLEQSTETNTGQQRATVPRWVQNL 1729
.|.|.| |.|.:..:| .||:|.: .:....| |....
Yeast 1353 FLNEKYIYQKASHLMQRFIE---------------------YLEKSLK----PEHVNTP-WFSKA 1391
Fly 1730 VDLIDAIDSISHILQRKANMRAVSSDVWRWYDASTGKWNAYSEANNELIRNAYAAGERWLYINIG 1794
:.:.:.|.:.|.: .::..:|.||...|
Yeast 1392 LYVYEIILAKSEL----PHLEELSKDVLLRY---------------------------------- 1418
Fly 1795 RQRCTVSLNCMTQVSEASGTHRPVCPALKLSEAITSLNNPVALHKVEHILNRVVRTAPDGSGTVH 1859
|.|.:: ||..| ||......
Yeast 1419 -------------------------PLLSMA-------------KVFRI--------PDPMKQKL 1437
Fly 1860 SDELISLRQLVNFTDGQQPQQSENSANPSEEATSEDGPAAANSGSPPATMTTRSKTRQKSAAAAA 1924
.|.||.:..:.||. |..|||. .:...|:.. .
Yeast 1438 FDILIRVSDISNFY--------------SALATSR-------------ILIFYSRDE-------L 1468
Fly 1925 AAKNKSQSGGSPPIPKRTQKIILNEEQVGLSKFDCGRIIGSIVDLLQPSHQMLNETKLSLLRLCA 1989
.|.|.::|| |..|..|:|.:.:::....| |..:.|.|.|.|.
Yeast 1469 YANNIARSG----ILSRLLKVIGSFQKLDKINF-------------------LESSFLLLTRRCF 1510
Fly 1990 RLTRNYDNAQVFIRRGGVRMLLHLQQACSFMGFPTYANIILRHVLEAPPVLQEAMERVLGMRAAG 2054
..|.|.| .:::..:.|....|..|
Yeast 1511 ETTENVD-----------------------------------------ALIRAEINRSFTARPLG 1534
Fly 2055 IVPVGHRDLIYVLTQVSSAVSRNPQIFVAAAKEMLKGEYLINTNSTTLADDARVMV----KSKFG 2115
......|:|..:|.:.:..|.|:|..|: :.|..|......||...:| |...|
Yeast 1535 GGDDAVRELTTILEEKAHVVMRSPSQFI---------DVLCETARFHEFDDQGALVDYSLKRFLG 1590
Fly 2116 QQPTAAAGGATPHNQTPTPPPAAKDELKDDPQVQSSVAVLKELLHGLV---QPCWHYGGTGSLDR 2177
::.......:|. |.| :.....::..||..|: :..|......|.|.
Yeast 1591 EKDKNTQASSTE---------------KSD--IYERTGIMHLLLSQLMAASEKDWLSEPANSSDL 1638
Fly 2178 GQGAAELLQPDQPPGTAQGCHDDELYFRFQETPAPVSSKKQSSSGGGAAAAGQTGQATEKFEPCC 2242
.:.....|.|.:.| .
Yeast 1639 PENKKAQLDPSRNP--------------------------------------------------V 1653
Fly 2243 CTWHIPTSGHTHAKPTISRATLLKLLADSTRAY-QSLVPRVLLSHVYTPADSPLISAPQQTFLGV 2306
|.:.| .|||||.:...:| |.....:..|...|.|:.| .|:.|.:..
Yeast 1654 CAYMI---------------FLLKLLVELVSSYNQCKFEFLTFSRRNTYAERP---RPRTTAINF 1700
Fly 2307 LLDRFL--PITQRHHVPE------VSTMTRVLICSLSDCYQQPGVQVHVAEELHAAVARALAQPD 2363
.|.|.| |:...|...| :..:.|.:|. |....|.::........||.|.
Yeast 1701 FLYRLLDKPVGTDHDKHEAKRREVIGMLARSVII---------GFLATVQDDRTTKTDVKLADPH 1756
Fly 2364 -SAEKHTRLQVLMSLFPNLIESPMLYDKVHMHRNNMYRVL----------LRQGVMTYLTKVAQY 2417
:..:...::.::....|...|..|.:..|:..:..:|:: |||.:.:...:..||
Yeast 1757 MNFIRKFAIEAIIKAIRNATSSSKLLESNHLKLDMWFRIITSMVYVQAPYLRQLLDSNKVEADQY 1821
Fly 2418 K------DLSNHNTLSTLAAILRPMEILLRFSVSTTTLGSKRILFGSGGPGGPNASGNGNNTAGG 2476
: ||...:.::...| |:......||:|
Yeast 1822 QLCKLVIDLGLPSVITEAMA-----------SIDLNYPFSKKI---------------------- 1853
Fly 2477 SSGNGPGSGNTYGTIINRRLYPRLAARTGFGSAMERSNAMGGEHVLRDIIRNVLSDRRHAFEFIF 2541
|..|:| ..|.:|..|:.|...|
Yeast 1854 -----------------------------FNVAVE--------------ALNTISSTRNNFSEHF 1875
Fly 2542 NSDDMAVDSEDAAAPGSGVGGGGSGAGSVGGGVSGSVSGNSSAAVIDVVEERSNGGDTNDPPANV 2606
..:|. |.||:..:..|..:.|
Yeast 1876 KIEDH-----------------------------------------DEVEDEVDESDKEEIP--- 1896
Fly 2607 SSASSGAGQSSTSGGPVRPVVNFDQLWDDFLQSEGLRLASRSGGGAGSGSGSVGASSSGQQNGSN 2671
|.|
Yeast 1897 ---------------------------DMF----------------------------------- 1899
Fly 2672 TTASSTNSGNNSGIGNLRLRTNPDVDVGSGNGSGSGSGSNAGVVNDNGISGGGGSDGASTSSDTG 2736
.||.:|
Yeast 1900 ---------KNSALG-------------------------------------------------- 1905
Fly 2737 APGGARDLNASLLGDVSTSESDSDPSTENDERNEEDEDEDDDAPDEDVDEHSETDVDEERSRQFI 2801
:.|| |:.|::|||......|:.:...||.:..
Yeast 1906 ------------MYDV-----------------EDIEEDDDDDTSLIGDDDAMAFVDSDNG---- 1937
Fly 2802 EVFDHIYEPESSETASNDADVDNDDDDDEDDVDDDDDDDEDNDDDVREEVQS--VMDAEIENRID 2864
|:.::. |.|||..|:|.||...|.|:| ::..|:|| ....:::..:|
Yeast 1938 --FEVVFS-------------DEDDDMGEEDADDARSDSEEN--ELSSEMQSSTADGTDVDYEVD 1985
Fly 2865 IALALVSSNNRPRRSAAVNASGDGSANRTNPDDEVDDEDDDVD----ADPDGDPDVDPISGPSAA 2925
.|..|:.:.::| ||| |:|:.|.|.::. ::.:.|..:|.|
Yeast 1986 DADGLIINIDQP--------SGD--------DEEMADYDANISHSSHSENEDDASMDVI------ 2028
Fly 2926 QAEAYLYERLGSGLMPTPPVGFRVRMNSSIAQPLDIDVNGGNAGSGSNAGATGSSGGSGQRSSTG 2990
|.| .:.|.| |:.|.:: |.||:..:..||.::
Yeast 2029 --EVY-DDELSS--------GYDVDLS-------DYDVDESDWDSGLSS---------------- 2059
Fly 2991 GTTASIGAIASAALRPSSGSWMAPDFNFIRISGGDSSMGSGPAIGGNANGGDMNVFITPSMSLER 3055
:.||..|
Yeast 2060 ----------------------------LSISDED------------------------------ 2066
Fly 3056 AGGAPGSGQTMSELLNEQPTGAGGGGGGGSASGVGGVGANGGTTGQHPNATLCTNGVRRRLLYLD 3120
||...::| .|....|......|...||..
Yeast 2067 -----------SESSEDEP-------------------INSTRMGDSRRRWLIAEGVEL------ 2095
Fly 3121 QQYCVCMPTHQNPTEETQMETFTQDALHWWLEEATLLDME---SQTDACLYAAHFLLPHLIKELK 3182
|:::|.|:...| ......:| |..:..|:..| .|::
Yeast 2096 -------------TDDSQGESEEDD-------RGVFRGIEHIFSNENEPLFRVH-------DEMR 2133
Fly 3183 AAHQQRKQEEAARQSTTPASGSNASATSSSTTSVVGTAAPTATSSIASGLLANAVSAGSGSSSLV 3247
..:..| |:..|...:|.|:.:..|| :.|..:.|.:
Yeast 2134 HRNHHR--------------------------SINRTHFHSAMSAPSLSLL----NRGRRNQSNL 2168
Fly 3248 VPPVAASATGGTRRSSIPVLISSTLGPSSASSATSATGNGATSDATTTTGGPTRNFSSVDSNVSS 3312
:.|: |||
Yeast 2169 INPL----------------------------------------------GPT------------ 2175
Fly 3313 ETQTTTRPPRQRGGLRQQSQLPFNIYAEIDLTNEQDSEGDRSTSTTTGTAADGAESQSQHNSSST 3377
||.| .|.|.|...| .|..|:..:|.|
Yeast 2176 -------------GLEQ-------------------VENDISDQVT--VAGSGSRPRSHH----- 2201
Fly 3378 AAQVAVPQHQRHPPVPLLPSSGRPSRPHTRLDETELLLLQLTDRQIRNRLQGSSGHTNSSRTSGS 3442
|..:|:|:
Yeast 2202 ------------------------------LHFSEVLV--------------------------- 2209
Fly 3443 ALINARPNRDLPACLQRHDHPAGSIFPRPSANRTPAPTLVSMPTPMSNAALEQ---LNVTAPDVV 3504
:||.|..|..:.....:.||....:.:...:. .|...|.|:
Yeast 2210 ---------------------SGSFFDEPVLDGIILKSTVSRWKDIFDMFYDSKTYANCIIPTVI 2253
Fly 3505 RTDRNFALPSSLEVDVDVLPGIVDLPQQEAQPEDDQLLLPPPPPPPPSDTTPLVHAEDDLWPGTV 3569
:|.:.:..:|:.|: |.:.|.::| ....|:..|
Yeast 2254 --NRLYKVSLALQKDL------------ENKREQEKL-----------KNKNLLFNE-------- 2285
Fly 3570 VSAGTREESSAPAVATESTEAVNESNQPEPTPESSESTSPNPQAPSAEPTPLEPGAAVDASVGAQ 3634
|.....:|:.|::.|..: :.||| .|.:..|......| |:.|| :|.
Yeast 2286 --AKVESHNSSDAISVEQDD-IQESN---VTHDDHEPVYVTIQ-----------GSEVD--IGG- 2330
Fly 3635 TPATTEEAASTAGASGTTATITDMSPEVRAALGDLEVPEGVDPSFLAALPSEMREEVIQEHLRMQ 3699
|| :||.|:.|||.::|.:|..:|:|.:
Yeast 2331 ---------------------TD-----------------IDPEFMNALPDDIRADVFAQHVRER 2357
Fly 3700 RIRQRAQQNAIQIAHDSLVEVNPEFLAALPLNIQSEVLMQQRIEQQRQAAQTANPEDPVDTAAFF 3764
|..|:.|:....|.. |::.:||.|
Yeast 2358 --RAEARLNSDHNVHSR--EIDSDFLEA------------------------------------- 2381
Fly 3765 QNLPENLRQAIL-TDMEE----SQIASLPPELAAEAQFLRRDWESRNGARMDAHPPSNALSRFQT 3824
:||::|:.|| |:.|| .:|.|....:.|:......|.|..|| :| |..||
Yeast 2382 --IPEDIREGILDTEAEEQRMFGRIGSSADVIRADDDVSNNDEEVENG--LD-HGNSN------- 2434
Fly 3825 TLQSLDDTRWHSSIWYDASGNAQPQHHQHTTIVHQHPHAHHAPNMGKPLALLMMEDENILLDPDS 3889
...||.|:..:...| :.|| |:|...
Yeast 2435 -----------------DRNNADPEKKKPARI-------YFAP----------------LIDRAG 2459
Fly 3890 LATLLLFLFVEDQKVNSMRLHRVIRNLCHHEPTRDWIISALISIIQKTNEDNANFGAGQAGGKPE 3954
:|:|:..:|:....:.....|.:...||..:..|:.:::..:.|:.:...|..:.
Yeast 2460 IASLMKSVFISKPYIQREIYHELFYRLCSSKQNRNDLMNTFLFILSEGIIDQHSL---------- 2514
Fly 3955 WLKLRVDAAFGYKSNIF-LINRLYEGSARSISINPQAAQMIVRNCLDLLFVLAKHYPSSFVPFNR 4018
..:: :|:....|.|::.:: :..||...|...
Yeast 2515 -------------EKVYNIISSRAMGHAKTTTV--------------------RQLPSDCTPLTV 2546
Fly 4019 DVKARRILSAVFGMPSPTAGSGGGAGSGSAASGGLTGYDDVPPGGTLDFRSRFCRYQVVNRLRSI 4083
..:...||.:: :|..||. :|.::
Yeast 2547 ANQTIEILQSL-----------------------------------IDADSRL-KYFLI------ 2569
Fly 4084 FDDHPAPKPSVPLDEAPSTSKAAAAKAAATAKVSTAGSQNKHSVPYQTNAKNFWDVVLNIDQQTQ 4148
|...::.:::|.:.|: |.::| :.|..|
Yeast 2570 -----AEHDNLIVNKANNKSR-------------------KEALP---DKKLRW----------- 2596
Fly 4149 VRLANVAQFPLTSQPAWEWQPNTADFLSFSESPFGQLLEMLPYKVICRSPHLTDML-------VK 4206
|.| .|..:|..|:|.....|.|:| .|
Yeast 2597 --------------PLW------------------HLFSLLDRKLITDESVLMDLLTRILQVCTK 2629
Fly 4207 LLASLSTELPKEEELLPLSDQMPPLVPIGPVQRAGAAAAAAHPPPPQPPAENTATATEIGDGLAA 4271
.||.|||....:|.|
Yeast 2630 TLAVLSTSSNGKENL-------------------------------------------------- 2644
Fly 4272 NIEEQASPASGNPASGDSNAGAKRTQLPTLSVALPVTPSKPRRKIYSKNFSQLQLVIEVLTHQCG 4336
:|:..|| |.:...|..::.::.....
Yeast 2645 ---------------------SKKFHLP------------------SFDEDDLMKILSIIMLDSC 2670
Fly 4337 TTEGLDNVAKLIVNLTQCSQASSAIFIQYLTAAILGLAEEVRQAIQMLLNEIRMYNIHQGGAGTT 4401
||........:|.||::. |...:||.::|.:..:.:..:::.|:..|..|: |..||
Yeast 2671 TTRVFQQTLNIIYNLSKL-QGCMSIFTKHLVSLAISIMSKLKSALDGLSREV--------GTITT 2726
Fly 4402 SQAASTSGAAAATASYVPTVSGASLLPNLAVHEGIMQDRFTAEHVIISAPKNAKPTCELQLPSMK 4466
....::......| :|:...|.||..|...: |...|......:|.|
Yeast 2727 GMEINSELLQKFT---LPSSDQAKLLKILTTVD------FLYTHKRKEEERNVK----------- 2771
Fly 4467 KLMSNSSAQPYFLRTLKIFMQVRDMYEAQNGLSTGGGVACGAGDNDDDIIDIEGDGGASGGSSSD 4531
.::.:|:..||
Yeast 2772 --------------------DLQSLYDKMNG---------------------------------- 2782
Fly 4532 MAPGSASTISPPPPMETNQIAQDGDDDEEDDDEARSFPGVGNHAVASASKSTKPTLSQILCLDVL 4596
.| :
Yeast 2783 ---------GP-----------------------------------------------------V 2785
Fly 4597 WNTLSECLVALEESKD-EFAVLVLQPTVEAFFLIHASHRGASKKSGRSFMPNAAGFGLRAAAGAG 4660
|::|||||...|:|:. ..:..:|.|.:|:..::
Yeast 2786 WSSLSECLSQFEKSQAINTSATILLPLIESLMVV------------------------------- 2819
Fly 4661 AIGGLGAAAPSAQEYSPFMDDVSSANTPSSASFDDEPRMQDASTNTPLVTNPSTSTAMSAHEAQL 4725
.|..|.|.| .:||:...:|:|
Yeast 2820 ------------------------------------CRRSDLSQN--------RNTAVKYEDAKL 2840
Fly 4726 RQDRQK------FLQFAEKHRTVLNQILRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQTELER 4784
.|..| |..|.:.|:.:|||::|.:| .|..||||:||.:.::||||.||.:|..:|:
Yeast 2841 -LDFSKTRVENLFFPFTDAHKKLLNQMIRSNP-KLMSGPFALLVKNPKVLDFDNKRYFFNAKLK- 2902
Fly 4785 LDEGIRREEHTVSVRRVTVFEDSFRVLYRLGPEEWKN-RFYIVFEDEEGQDAGGLLREWYVIISR 4848
.:...|.:..::|||..||.||:|.|:....:|.|| :..|.|:.|.|.||||:.||||.::||
Yeast 2903 -SDNQERPKLPITVRREQVFLDSYRALFFKTNDEIKNSKLEITFKGESGVDAGGVTREWYQVLSR 2966
Fly 4849 EIFNPMYALFCVSPGDRVTYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHI 4913
::|||.||||...|.|:.|:..|.:|..||.|||:|||:|.:|.||:.|...|:|:|:|..||:|
Yeast 2967 QMFNPDYALFLPVPSDKTTFHPNRTSGINPEHLSFFKFIGMIIGKAIRDQCFLDCHFSREVYKNI 3031
Fly 4914 LGKQVKHTDMESQDYEFYKGLDYLMKNDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAVTEE 4978
||:.|...||||.|.::||.|.::::|||:.: .|.|||.|..::|..::.:|...|:|..|||.
Yeast 3032 LGRPVSLKDMESLDPDYYKSLVWILENDITDI-IEETFSVETDDYGEHKVINLIEGGKDIIVTEA 3095
Fly 4979 NKFEYVQLVCQLKMSGSIRQQLDAFLEGFYDIIPKHLISIFNEQELELLISGLPDIDIEDLKANT 5043
||.:||:.|.:.|:..|:::|:|.||.|||.:|.|.||:||:|||||||||||||||::|.|.||
Yeast 3096 NKQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDLITIFDEQELELLISGLPDIDVDDWKNNT 3160
Fly 5044 EYHKYTSKSAQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMNGIQKFQIHRDDRS 5108
.|..||:...::.:||||:||||..:|||.||||||||||||.||..|.|:||:.||.||||..|
Yeast 3161 TYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFGS 3225
Fly 5109 TDRLPCAHTCFNQLDLPMYKSYDKLRSCLLKAIHECSEGFGFA 5151
::|||.:|||||||:||.|:||:.||..||.||:|..||||.|
Yeast 3226 SERLPSSHTCFNQLNLPPYESYETLRGSLLLAINEGHEGFGLA 3268
| 
