DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8097 and Rars2

DIOPT Version :9

Sequence 1:	NP_001285279.1	Gene:	CG8097 / 32495	FlyBaseID:	FBgn0030660	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_852071.2	Gene:	Rars2 / 109093	MGIID:	1923596	Length:	578	Species:	Mus musculus

Alignment Length:	232	Identity:	61/232 - (26%)
Similarity:	96/232 - (41%)	Gaps:	63/232 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 RCQHMEL-----MATQRSGMCPVP-------------MSSLDT---------LTKRLAAAAVIVD 285
            ||||:..     |.|:|.|:..:.             |:|:.|         ..:|:..||||:.
Mouse   371 RCQHVPFGIVKGMKTRRGGVTFLEDVLNEVQSRMLQNMASIKTTKQLENPQETAERVGLAAVIIQ 435

  Fly   286 LFVVRHS---------SAVSVVRNGVGICKGASYILYNSARLEALLRKFNYEVNNCAYEKLPLLD 341
            .|  |.:         ..|...|...|:     ::.|..|||.:|...|     .|.|     |:
Mouse   436 DF--RGTLLSDYQFSWDRVFQSRGDTGV-----FLQYTHARLCSLEETF-----GCGY-----LN 483

  Fly   342 EIDLSVLEDDVDWELIYGYLLTFPELMESIMDQLDQGHCGLHLLVHYVENLAAAFSRFYYHKKVL 406
            :.:::.|::.....::. :||.|.|::......|...|...:||.  :.:|||.     .||  .
Mouse   484 DSNVACLQEPQSVSILQ-HLLRFDEVLYLSSQDLQPKHIVSYLLT--LSHLAAV-----AHK--T 538

  Fly   407 LQKRDELMPILYARIYLIKAVRQVLNTALAVLGIEPV 443
            ||.:|....:..||::|.||||.||...:.:|||.||
Mouse   539 LQVKDSPPDVAGARLHLFKAVRSVLANGMKLLGITPV 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8097	NP_001285279.1	DALR_1	311..445	CDD:214846	40/133 (30%)
Rars2	NP_852071.2	ArgS	30..578	CDD:223097	61/232 (26%)
		ArgRS_core	126..388	CDD:185675	6/16 (38%)
		'HIGH' region	133..144
		L-arginine binding. /evidence=ECO:0000250\|UniProtKB:P54136	133..135
		Anticodon_Ia_like	425..578	CDD:299868	50/178 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810