Protein Alignment CG8097 and Rars1

DIOPT Version :10

• Sequence 1: NP_573046.1
• Gene: CG8097 / 32495
• FlyBaseID: FBgn0030660
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_080212.2
• Gene: Rars1 / 104458
• MGIID: 1914297
• Length: 660
• Species: Mus musculus
• Alignment Length: 519
• Identity: 107/519 - (20%)
• Similarity: 185/519 - (35%)
• Gaps: 171/519 - (32%)

  Fly    12 QLFEFFTKPEKPDESGGDVAAPLLLK-------KFGKLIRYNNDDLTEQ-------GDLTLAAIP 62
            :||||         :|.||   |.|.       :||.||.:..|...:.       |||
Mouse   223 RLFEF---------AGYDV---LRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDL------ 269

  Fly    63 RYWQKYLKSQGLKLRIDGDELLPSPVDRLELMEHSRK------WR-------------FPLAEIT 108
               |.:.|..  |.|.|.||.......:..::..|:.      |.             :...:||
Mouse   270 ---QAFYKES--KKRFDADEEFKKRAYQCVVLLQSKNPDIMKAWNLICDVSREEFKKIYDALDIT 329

  Fly   109 VLNKER--YSLRFQ-----------------RHPIIAHVLNSVLTL-RGDYGRSANNNQSRTICL 153
            ::.:..  |..|.:                 |..:.....:..||: :.|.|.:.:.:....|..
Mouse   330 LIERGESFYQDRMKDIVKEFEDKGFVQVDDGRKIVFVPGCSVPLTIVKSDGGYTYDTSDLAAIKQ 394

  Fly   154 QL-----QAVVGAVDGGQDLRHYR-----LQQL--YKILLRLVDYSSWRLVEPNDRQK------D 200
            :|     ..::..||.||.: |::     .|.:  |...:.||.:..:.:|...|::|      :
Mouse   395 RLFEEKANKIIYVVDNGQAI-HFQTIFAAAQMIGWYDPKVTLVTHVGFGVVLGEDKKKFKTRSGE 458

  Fly   201 TICVTVELEKCCNGKQPVEHVCLTCGPVLEPINKGASSLTVDEYLKLRCQHMELMATQRS---GM 262
            |:.:...||                    |.:.:....|...|..|:..:. ||.|.|.|   |.
Mouse   459 TVRLMDLLE--------------------EGLKRSMDKLKEKERDKVLTEE-ELKAAQTSVAYGC 502

  Fly   263 CPVPMSSLDTLTKRLAAAAVIVDLFVVRHSSAVSVVRNGVGICKG--ASYILYNSARLEALLRKF 325
            ......|.:.|...:.:...::|                   .:|  |:|:||...|:.::.|..
Mouse   503 IKYADLSHNRLNDYIFSFDKMLD-------------------DRGNTAAYLLYAFTRIRSIARLA 548

  Fly   326 NYEVNNCAYEKLPLLDEIDLS--------VLEDDVDWELIYG-YLLTFPELMESIMDQLDQGHCG 381
            |             :||..|.        :|:.:.:|:|  | .:|.|||:::.|:|.|     .
Mouse   549 N-------------IDEAMLQRAARETKIILDHEKEWKL--GRCILRFPEILQKILDDL-----F 593

  Fly   382 LHLLVHYVENLAAAFSRFYYHKKVLLQKRD--ELMPILYARIYLIKAVRQVLNTALAVLGIEPV 443
            ||.|..|:..||..|:.||.....:.:.|.  :::.:...|:.|.:||..|:.....:|||:||
Mouse   594 LHTLCDYIYELATTFTEFYDSCYCVEKDRQTGKVLKVNMWRMLLCEAVAAVMAKGFDILGIKPV 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8097	NP_573046.1	DALR_1	311..445	CDD:214846	39/144 (27%)
Rars1	NP_080212.2	Could be involved in the assembly of the multisynthetase complex	1..72
		PLN02286	80..660	CDD:215160	107/519 (21%)
		'HIGH' region	201..212
		Interaction with tRNA. /evidence=ECO:0000250|UniProtKB:Q05506	529..543		5/13 (38%)