Protein Alignment cerv and Nsmce2

DIOPT Version :8

• Sequence 1: NP_001285278.1
• Gene: cerv / 32492
• FlyBaseID: FBgn0030657
• Length: 230
• Species: Drosophila melanogaster
• Sequence 2: XP_006521379.1
• Gene: Nsmce2 / 68501
• MGIID: 1915751
• Length: 273
• Species: Mus musculus
• Alignment Length: 277
• Identity: 59/278 (21%)
• Similarity: 103/278 (37%)
• Gaps: 84/278 (30%)

  Fly     7 VDSALTTLLENQKFFKEMAEVVSDFSDGREIQKLLDQNVDLAENLIRMKSKHQLLSKAM------ 65
            ::|||::|...|.......:.||..:            :||.|....:.|::. :.|||
Mouse    20 IESALSSLKNFQSCISSGMDTVSSVA------------LDLVETQTEVSSEYS-MDKAMVEFAKM 71

  Fly    66 -----KHAKNSSNTIEKFEEVWKERSEAVEQKRIDV---------KNS-AEFKNFMKAAA----- 110
                 .:.|...:||...:|   ||.|.|...::.|         ||| |:||...|...
Mouse    72 DRELSHYVKAVQSTINHVKE---ERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQFKQQL 133

  Fly   111 --------------------PQAGAETNGQANSAAH-----------DEDLIMEATGGEVFSLYD 144
                                |...:...|......|           |||:|:..:......
Mouse   134 RELKKQLVKPKEDGRHSEFDPNKDSSRAGNKRDGIHADRENDLTEGVDEDMIVTQSQTNFIC--- 195

  Fly   145 PWSKALIKNPVRNKKCGHIYDRDSVMLIITDNIGIR----CPVLGCPNRSYIHPAHLVKDSNLQQ 205
            |.::..:|.||:||.|||.|:.::::.:|......:    ||.:|| :.:.:..:.|:.|..|::
Mouse   196 PITQLEMKKPVKNKMCGHTYEEEAIVRMIESKHKRKKKACCPKIGC-SHTDMRMSDLIPDEALRR 259

  Fly   206 KLQERMSDAIEKETSSE 222
            .::   |...:|:..||
Mouse   260 AIE---SHNKKKKRHSE 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cerv	NP_001285278.1	RING	128..186	CDD:302633	17/62 (27%)
Nsmce2	XP_006521379.1	zf-Nse	182..242	CDD:288622	18/64 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG2979
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I5405
Isobase	1	0.950		0	Normalized mean entropy	S7995
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0002478
OrthoInspector	1	1.000				T616931
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR21330
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5680
TreeFam	1	0.960
	9	8.900