Protein Alignment Gmap and trip11

DIOPT Version :10

• Sequence 1: NP_001356946.1
• Gene: Gmap / 32483
• FlyBaseID: FBgn0027287
• Length: 1401
• Species: Drosophila melanogaster
• Sequence 2: XP_031747520.1
• Gene: trip11 / 448517
• XenbaseID: XB-GENE-5935911
• Length: 1954
• Species: Xenopus tropicalis
• Alignment Length: 2004
• Identity: 442/2004 - (22%)
• Similarity: 787/2004 - (39%)
• Gaps: 682/2004 - (34%)

  Fly     4 LNSSLSQLKGQLTNLAQEVLAETAGP-GDLEYEGHQAGGASVQDA-----------EQQAKTALE 56
            :..|||.:.||::|..:::|.|.|.. ||:..| .|...:.::|.           |:..|...|
 Frog    19 VGGSLSSITGQISNFTKDMLLEGAEEVGDVNTE-LQVSNSKLRDIENVQTMQRSENERLRKLCTE 82

  Fly    57 L-----LAETQEQKEQLD--KRCEEKDREIAALRREL-AKSKQKQESQLAASTSATREPQLQNEE 113
            |     .||.|.:::.||  .|.::|:.|::.|:.:| |..:|.|:.|.:|        ||....
 Frog    83 LEEKHETAELQVKQQSLDFRNRLQQKEVEVSHLKAKLNALQEQMQKMQASA--------QLAGVT 139

  Fly   114 PNVEDSWCWEPDGGDEKGATGAGSGDSASRDKESGLVDIALGNDDVVRLNNRIAELE-------- 170
            ....::..:.|   ..:....|..||    |.:.|  |:.....::.||::.::.||
 Frog   140 LQTINTSSFMP---TSQTPVSAFQGD----DMDFG--DVIWSQQEINRLSSEVSRLESELAHWKQ 195

  Fly   171 --------------------------QLNEQLNVSLEELDSQHEL-----AMRDVL-----EHKT 199
                                      :|.::|:..::|  .||||     |.|..|     .|:.
 Frog   196 IAQAPKSQGTQKTDTNEICVLQNVIKELKQKLSHEIDE--HQHELSVLQDAHRQKLTEITRRHRE 258

  Fly   200 QLAGQVASLKQLQADRLVEHELSNARQQKQLDELRQTSSAAKKQQEELQRRVEQQEAELIEMQDL 264
            :|......:::|: ::|.....|....|.::.||::...|.:.::||...|:::.|.::|.|.:|
 Frog   259 ELGEYEERIEELE-EQLQPGTSSEVTDQSKVLELQKRIQAIELEKEENTSRIQELEDKIIGMNNL 322

  Fly   265 L-------------------DKRRQDTAELIERVRV-----------AETERERLLKD----LEE 295
            :                   :|.|.  |:..|::::           |::|:..||::    |:|
 Frog   323 ITSLENEKHSVVKDHKEAVDEKNRM--AQNYEKLKLEIANQESVGESADSEKVILLQEEVRQLQE 385

  Fly   296 TRQAKEKKTSESSSNSSSTGK----------------HSEDEFIVV------RQADATGSGSASG 338
            ....||:|:..|:....:|.|                |.|::.:::      |:.|..    .|.
 Frog   386 ALHEKERKSRSSADQQDATLKEESLKNLELENKLMAFHEENKKLLIDKEELQRKLDIV----QSA 446

  Fly   339 SDRDPDADV-TSPPSKE------KLRDRL---VSLESQISELTLANTQ------LQDAQLEK--- 384
            ::||.|.:: ....|||      |::|..   .||.:::.||...|.:      |...||.|
 Frog   447 ANRDSDLELKLQQLSKELEESQLKVKDNYEEKKSLSAELEELDKQNQEAMQHLLLMKEQLSKHRD 511

  Fly   385 --QLSINMLGEQLVELEKRLRLSEAEKEQLQV-----------------NLQLRLQQLTVQNQEL 430
              :.||..|.|||...:|:...:|.|.:.||:                 .:|:..|||:.:.|||
 Frog   512 EMETSITHLQEQLENEKKKFSDAEMENKDLQIKFRIQEDKLSQSLELYNTMQVTNQQLSFEVQEL 576

  Fly   431 -----------------------KLHAEAEQEGHAQNLEEQL-----GD--------LREDNQRL 459
                                   ||....||....::|.:.|     ||        |.|.|| :
 Frog   577 ISKLETMENSNIGIKRENQELQEKLKQVTEQLSRIESLPQSLDTSKVGDEPEKLITELSEINQ-I 640

  Fly   460 RQELKTSI----------------AQAKFRQAIAE------EKQEI------------TDLDDAD 490
            ::||:..|                .:.||.:.||.      ||:.|            |:|:.::
 Frog   641 KEELEKVICDLKMENEMLLSTQEQTKVKFEETIATKNKDSLEKKTIIEALRMEKCRLETELNQSE 705

  Fly   491 SEYGTFELDKLRALLQAE-----IED-----RLDSSFPQQKLERAWNALKDRWHRL----DLVEQ 541
            :          |.|.||:     ||:     ::|:|..|::.||.....::|..:|    .::||
 Frog   706 N----------RLLDQAQKYEHTIEELSAAQKMDTSALQREHERLLKLNQERDFQLAESKRMIEQ 760

  Fly   542 ------RLVDVQNQQLVSE-------HEKKTL-------EADISQYILQCDELMKNNDLLLNELD 586
                  ...::.|..||.:       .||:|.       ..::.:.|.|..:..|..:||...::
 Frog   761 IENDYEETKEILNSSLVGQKQLAELLKEKETFVEQLKERNTELQEEIEQLSKTSKERNLLRQNIE 825

  Fly   587 KYKRNKLETIEE---HHEETIVQLEAQLEEARQKLELASLSSQQQMETHLIS-SPEKTPVDSEL- 646
            : |...|.:::|   |.:|.|.:|:.|...::..:|..:|....::|..:.. :..:...:.||
 Frog   826 E-KDKSLASMKEENNHLKEEIERLKDQQSRSQAAVEPKTLDIITELEAEITQLTKVRNSYEEELK 889

  Fly   647 LAKMEQKEQEY--LQLQEQLAFAKTELDK-----------RNKLLERNGEQLTKQQQQN------ 692
            |.|...::|.|  :|||:.|.....|:|:           ..|||.....:::..||.|
 Frog   890 LQKKAVEKQNYSTMQLQQTLQEKTKEMDEVKLQQKQTVDTYEKLLSEKDSEISSLQQTNELISSQ 954

  Fly   693 ----------------------------------------------------------------- 692
                                                                             
 Frog   955 LQSEHVYHTQSSVILPDTKTQTMNGENGVEKHDLSKAEIERLVKGIKEKEMEIKILNEKNSTLSK 1019

  Fly   693 QADQKKLEELSQLRETLQRRD----------------EDLKELEEQLSAVRQD-------LDEKS 734
            |.||...:|:::|.:.:|::|                :|:..|::||.|...:       |.||:
 Frog  1020 QIDQLSKDEVAKLTQIIQQKDLEIQTLHARVSSVTYMQDVVYLQQQLQAYAMEREQVLAVLSEKT 1084

  Fly   735 IQ-MKISQDQHKLQ---------LANLQNQLQ--------ADQEKLRELLQLQDKLEQQKELMEV 781
            .: .::..:.||:.         |..||.:.|        :.|:..||.:|...::.::|:: |:
 Frog  1085 RENSQLRTEYHKIMDVMAAKESALLKLQEENQRMSHTQEGSTQDMFRETIQNLSRIIREKDI-EI 1148

  Fly   782 DQNQQ-----ITIIKKEL--------AETTNQLSE-CQERLTVKE--AQLAEIQQQ----LQEVN 826
            |...|     :|:::...        :..:||..| .|||..:|:  .::.|.:||    :|.:.
 Frog  1149 DALSQKCQTLVTVLQTSTSGNSNEPGSVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQ 1213

  Fly   827 EERTRLQEQLLTKEQESGLDSELAKRNQELEDQLL----AKEQQLQLNQAELEKLQET---LRVN 884
            .|...|||:|...:.:..:||:.:.:.|.....|:    ..|::|:....||..:|.:   |..:
 Frog  1214 HESAHLQEELHKLQGQIAVDSDSSSKLQVDYSSLIQSYERNEEKLKGLSVELSNVQHSIGQLNSS 1278

  Fly   885 EEQLLAKEEQLH------------------------------------------AKESQLQSL-- 905
            :|.||.|.|.:|                                          .:|:.:::|
 Frog  1279 KEILLCKLETVHPQSNTTSTGSVSESLAVVGNDQLSDQIKPVLQECERLKMEVQKQEAIIRTLQE 1343

  Fly   906 ---------------------ESQLQGQLAADESQQLQQTIDGLGQEKNELIKV----------- 938
                                 ||.|..::..::::|||:::    :||:.|||.
 Frog  1344 NNQRLSDSLASVSEQGRKGQEESTLGLRIVKEKNEQLQKSL----KEKDLLIKTKGDKLNSVNEN 1404

  Fly   939 LQQKHQENTQYYAEIQRLQP----FEQQVKELVKEREK-----LQDQVGF--------------- 979
            |:.|..||......:..|:.    .|..:::|.:|.||     ::.:..|
 Frog  1405 LRSKENENELLKQAVTNLKERTLILELDIRKLKEENEKIMAKGMEKETEFRALHETNMQFSMMLR 1469

  Fly   980 --------LKEKSDILTTNLLTE-------QTNQRL-----------------------LQQQQA 1006
                    :|||:..| .|||.|       :.||.|                       |:|:|.
 Frog  1470 EKEFESTSMKEKASAL-ENLLKEREQGKAGELNQLLNEVKSMQEKAVLFQHERDQVMLVLKQKQM 1533

  Fly  1007 E--SQEQQASTLRD--------LERLRAHLLEIEELHTQETVELQRDLEESRSRQAILEQQVSKS 1061
            |  |.:.:...|||        |:|||.||||:|:.:|:|.|..:....|.|.:.:.||.::..|
 Frog  1534 ESVSLQNEVQHLRDKEQRLNQELDRLRNHLLEMEDSYTREAVAAEDRETELRKKVSRLEDKLLSS 1598

  Fly  1062 STAYTSASIRANQQAETLQAQHALLQQQRDELLAKLGQYEDRELKQQA-ALTNLQCALEQFQNDK 1125
            |:|..:||.:|:.|.|:||.|..|..:||||.|.:....:: :.||.| :|.|||..|||||.::
 Frog  1599 SSAVENASHQASMQVESLQEQLNLASRQRDEALLQFNLSQE-QCKQYALSLANLQMVLEQFQQEE 1662

  Fly  1126 DHDIEMATQRIRREMQAQLDRQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRD 1190
            ........::.:::......:...|:.:...|:::|.|||..|.:|:||::||:..::.|..|:.
 Frog  1663 KAMYSAELEKHKKQACELKQKVEILENKALSLKEKLDEANVALESASRLTEQLDIKEELIEELKR 1727

  Fly  1191 E----VESLKEANGQLEQRLSSSESSQTDKIDKSLIKSLLIGYVVSGHA--GDKQQVLRMISSVL 1249
            :    .|.|::|..:|...|:|:|.    |:||.|:::|.:|:.   |.  ..:.:|||::.|:|
 Frog  1728 QGDLKQEMLEDAQNKLMNLLNSTEG----KVDKVLMRNLFVGHF---HTPKNKRHEVLRLMGSIL 1785

  Fly  1250 DFNAQEADKV------GLNKQQSSWLGAILGGGSATASAAGS-----SRGNENLVQAFVQFLEQE 1303
            ....:|.|::      |:::..:.|||   ||||.:..:...     |..|.:..:.||:|||.|
 Frog  1786 GIKKEEMDELVVDEHRGVSRWMTGWLG---GGGSKSVPSTPQRPNHPSLFNTSFSELFVKFLETE 1847

  Fly  1304 SQPQAQSRPTLLSMTGQMDGVT----------SASATTSTAAT--SGHLPQASSSF----SPATP 1352
            |.|    .|..|.:|  |..:|          |.|..||.|.|  ||...|.|:.|    |.|.|
 Frog  1848 SHP----TPPPLKLT--MQELTPSRPASTLNPSGSLATSVAGTMVSGSRRQESNPFLAPRSAAVP 1906

  Fly  1353 AASQQDPAAPRTPPVGGSP--QLLAMGSNEFAPT---------RNSSSILKDIL 1395
            ..|        |..:|||.  .||....::..||         .::.::|||:|
 Frog  1907 LIS--------TSSLGGSASGHLLMKPISDALPTFTPLPVSSESSAGAVLKDLL 1952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmap	NP_001356946.1	SMC_prok_B	169..973	CDD:274008	248/1287 (19%)
		Smc	<645..>1195	CDD:440809	183/855 (21%)
trip11	XP_031747520.1	rad50	<56..494	CDD:129694	93/463 (20%)
		SMC_prok_B	<285..1043	CDD:274008	153/775 (20%)
		SMC_prok_B	775..1744	CDD:274008	206/976 (21%)
		GRAB	1749..1791	CDD:431241	14/48 (29%)