Protein Alignment mh and Sprtn

DIOPT Version :8

• Sequence 1: NP_573032.1
• Gene: mh / 32480
• FlyBaseID: FBgn0267977
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001104611.1
• Gene: Sprtn / 244666
• MGIID: 2685351
• Length: 497
• Species: Mus musculus
• Alignment Length: 565
• Identity: 183/566 (32%)
• Similarity: 268/566 (47%)
• Gaps: 129/566 (23%)

  Fly    76 ENSEIKNKKREAAKKKPVRAIQASHDDYLNKTMNLVDPEWELVDPTPDIYAMFIRFDEKFFQERL 140
            |..:::..:|.||.::||               :|||..|||||||||:.|:|::|:::||..:|
Mouse    13 EEWDVQMARRAAAAREPV---------------SLVDASWELVDPTPDLQALFLQFNDRFFWGQL 62

  Fly   141 GAVSLEWSKKMYSCAGICYQRGNRFVKQVTIRLSEPLLKLRPRKDLVETLLHEMIHAYCFVLNIR 205
            .||.::||.:|..|||||...|..  ...:||||||||||||||||||||||||||||.||.|..
Mouse    63 EAVEVKWSVRMTLCAGICTYEGRG--GMCSIRLSEPLLKLRPRKDLVETLLHEMIHAYLFVTNND 125

  Fly   206 EGNGGHGPNFKRIMETINKVAGTNITVYHTFHDEVASYRTHIWRCTGICRERSPFWGYVKRTSNR 270
            :...||||.|.:.|..||::.|.||||||||||||..||.|.|||.|.|:.|.|::|||||.:||
Mouse   126 KDREGHGPEFCKHMHRINQLTGANITVYHTFHDEVDEYRRHWWRCNGPCQHRQPYYGYVKRATNR 190

  Fly   271 APGPNDQWWKMHQRECSGTFLKLSEPPK-APKPETKSRAKKSTPAVAAPKEDIRNWFGQPSAKKA 334
            ||..:|.||..||:.|.||::|:.||.. :.|...|::|.|. ||.|...:|
Mouse   191 APSVHDYWWADHQKTCGGTYIKIKEPENYSKKGRGKTKADKQ-PASAVENKD------------- 241

  Fly   335 ATGTVLLGDLAKAVPPTSYPGLSSEPFAL---PKTPAAGTKGNKSGGFNELDKSGSKATTEMSGQ 396
               .:..|:....:|      .|.:.:.|   ...|:|| |.|.|...||        ...:|.|
Mouse   242 ---KLCRGEAQLLIP------FSGKGYVLGDASTCPSAG-KLNTSYMVNE--------AKGLSSQ 288

  Fly   397 GYSLGGSSAIEHIDLSDTDVPDSAKLRQIRLQRFSEDASNKRQNKKKRRRVS-----SDSEIINW 456
            .:|:.|                      :||...:|....:....||...||     |...:::
Mouse   289 DHSVSG----------------------LRLNSNAEVKCEQNCLPKKPHLVSPLPTASHQSVLS- 330

  Fly   457 ESYDDDVMV------RDVH-TPIVN------LVESSSDEEEMKMPAGRKTMTSQERTQIIKRQVM 508
             ||...|.|      |:|: :|:.|      ....:|...:.|:|..|.::.:..:........:
Mouse   331 -SYFPRVSVANQKAFRNVNGSPVKNGTTGDGTKRPASGGSQRKVPPSRASLRNTSKVTAPASATV 394

  Fly   509 EDELTLCEDDILLIDDEYDDEVAANESLTAATELA---DQSI-----IDDIFGEDTLLKEFQREN 565
            ..                    ||..|.|.:.|.:   ||.:     ::|....||:.::.|...
Mouse   395 TS--------------------AAGTSATISREESGSEDQFLNKRPRLEDRTALDTIKEQTQSGG 439

  Fly   566 DV----QPSCSSYAKRIEND--IVSCPICFEKMRRTELSNHFDGC 604
            |:    ||:.:|..:.:.:.  :|:||:|...:..::::.|.|.|
Mouse   440 DLRSSSQPTAASAPQSLSSQRRLVNCPVCQGVVVESQINEHLDRC 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mh	NP_573032.1	SprT-like	124..294	CDD:287265	97/170 (57%)
		ZnF_Rad18	582..605	CDD:128973	7/24 (29%)
Sprtn	NP_001104611.1	SprT-like	46..214	CDD:287265	97/170 (57%)
		SHP-box	254..262		2/8 (25%)
		PIP-box	326..333		2/9 (22%)
		ZnF_Rad18	462..485	CDD:128973	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C147078045
eggNOG	1	0.900				E1_KOG3931
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004771
OrthoInspector	1	1.000				T1085222
orthoMCL	1	0.900				OOG5_130345
Panther	1	1.100			LDO	PTHR21220
Phylome	1	0.910		0.857	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3918
TreeFam	1	0.960
	9	8.730