Protein Alignment CG9519 and chdh-1

DIOPT Version :10

• Sequence 1: NP_572978.1
• Gene: CG9519 / 32415
• FlyBaseID: FBgn0030589
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 201/620 - (32%)
• Similarity: 295/620 - (47%)
• Gaps: 112/620 - (18%)

  Fly    50 ENLDEG----QVITTKYDFIVVGAGTAGCALAARLSENPRWRVLLLEAGGPENYAMDIPI----- 105
            :::.||    .:...|...|:||||:|||.||.||:|:|..||||:|| ||.::..|..|
 Worm    22 DSMKEGTFSADIAENKPTHIIVGAGSAGCVLANRLTEDPSNRVLLIEA-GPVDHKWDWRIHMPAA 85

  Fly   106 VAHLLQLGEINWKYKTEPSNSYCLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWARLG 170
            :.:.|.....||.|.|....:    :.|....||||:|.||||.||.|.|.||:..||:||.:.|
 Worm    86 LMYNLCSDTYNWHYHTTAQKN----LGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEG 146

  Fly   171 NPGWSYEEVLPYFKK---YEGSVVPDADENLVGRNGPVKVSYSETRTRIADAFVGATQDAGLPRG 232
            ..||:|...||||||   |..:..|  ::...|.|||:.|...:....:..|::...::.  |.|
 Worm   147 ASGWNYANCLPYFKKAETYSDATGP--NDPYRGNNGPLYVKKGDAENPLHKAWLNVGKEH--PLG 207

  Fly   233 ---DYNGDKQIRVSYLQANIYNETRWSSNRAYLYPIKGKRRNLHVKKNALVTKILIDPQTKSAFG 294
               |.||:||..:|.:...|:|..|||:::||::||: .|.||........|::|.|  |..|.|
 Worm   208 WTNDMNGEKQEGISTMDMTIHNGERWSASKAYVHPIR-NRPNLITSSGITCTRVLFD--TNKAIG 269

  Fly   295 I-------IVKMDG----KMQKILARKEVILSAGAINTPQLLMLSGVGPAKHLREMGIKPLADL- 347
            |       .|..|.    ..:||..:.:|||:.|||||||||||||||||.|||...|..:|:|
 Worm   270 IEFIRKLNFVGTDSIDSYSREKIYCQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLP 334

  Fly   348 AVGYNLQDHIAPAISFLCNVSSLQTSEMFRSEAMSDFLKGRGVLRIPGGVEAISFYALDDARNPD 412
            .||.|||||:                |::..:.               ..:.::.|      |..
 Worm   335 GVGQNLQDHL----------------EIYVQQE---------------STQPVTLY------NKS 362

  Fly   413 AWA-DMELFVVGGGLQTNLALRLALGIQSNIYETMFGELE-----------------------RQ 453
            :|. ...:..:|....||   |..||..|::....|...:                       ..
 Worm   363 SWKFPHNMIKIGLEWFTN---RTGLGASSHLETGGFARSDDTVTHPDIQFHFLPSTVHDDGRTNG 424

  Fly   454 SANGFLIFPMILRAKSRGRIKLKSRNPEEHPRIYANYFANPYDMNITVRGIEQAVSLLDMPAFKA 518
            :.:|:.:....:|::|:|.|.|::::|...|.|..||.....|.....:.|..:..|....||..
 Worm   425 TCHGYQVHVGPMRSQSKGYIMLQAKDPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDE 489

  Fly   519 I-GAHLLEKRIPNCAKYKWKSSAYWACYARHFTFTIYHYSGTAKMGPRSDPSAVVDAR-LRVHGI 581
            . |..|...  |:|     :|.|....:.:....:.||.|.|.|||..:|..|||:.. :.|:|.
 Worm   490 FRGKELAPG--PDC-----QSDADIDRFVKEKAASAYHPSCTCKMGSENDKMAVVNPETMGVYGT 547

  Fly   582 DKLRVVDASIMPYLISGHPNGPVYLIAEKAADMIK 616
            :.|:|||||:||.::||:.|.||.::||:|||:||
 Worm   548 ENLKVVDASVMPSIVSGNLNAPVIMMAERAADLIK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9519	NP_572978.1	BetA	59..619	CDD:441878	199/607 (33%)
chdh-1	NP_495846.1	Rossmann-fold NAD(P)(+)-binding proteins	41..599	CDD:473865	198/601 (33%)