DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5321 and Bbox1

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_072151.1	Gene:	Bbox1 / 64564	RGDID:	619756	Length:	387	Species:	Rattus norvegicus

Alignment Length:	362	Identity:	141/362 - (38%)
Similarity:	210/362 - (58%)	Gaps:	9/362 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWL 113
            :|.:||||||.|.||:..|:|:|||..:..|..||...|..|:  |:|.:.|.:.|.|.|...||
  Rat    29 YPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRMDDLTFDQ--KKVYITWPNGHYSEFEANWL 91

  Fly   114 KERCFEPDKQQEYLRDFYRPTTRHWSGAEFQDIAQHFSYDEVMSQDSVLMQWLQALAIYGVALLR 178
            |:|||..:.:.....:.:.|..::| |:|.|  ....::::|::.|....:||.:|...|:..|.
  Rat    92 KKRCFSQEARAGLQGELFLPECQYW-GSELQ--LPTLNFEDVLNDDDHAYKWLSSLKKVGIVRLT 153

  Fly   179 GAPLDEGVVRRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILH 243
            ||....|.:.:|..|:||:..|.||..:.||.|..|.|.||.:..|..|||.|...:.|.|.:||
  Rat   154 GAADKRGEIIKLGKRIGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLH 218

  Fly   244 CVVQTDSPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHNIWRAPVICLD 308
            |:.||.: ||.:.:||||:|...|:..:|:.|..||...||:.||| .|..:|....:..:|.||
  Rat   219 CIKQTVT-GGDSEIVDGFNVCQKLKEKNPQAFSILSSTFVDFTDIG-VDYCDFSVQSKHKIIELD 281

  Fly   309 EEGRYTRINHSVPQRDSHFNVPLEEVLPWYESYALFVRLAIAD--SHAFKTRPGDVLTFNNIRLL 371
            ::|:..|||.:...||:.|:||:|.|.|:|.:...||.|..:.  .:.||..||||:||:|.|||
  Rat   282 DKGQVVRINFNNATRDTVFDVPIERVQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLL 346

  Fly   372 HGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLKKRL 408
            |||..|:...|..|::.|||.|||::.||||:|::|:
  Rat   347 HGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRV 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	26/63 (41%)
		carnitine_bodg	49..405	CDD:274118	139/357 (39%)
		CAS_like	127..395	CDD:238154	101/269 (38%)
Bbox1	NP_072151.1	CAS_like	16..381	CDD:412204	140/358 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346530
Domainoid	1	1.000	168	1.000	Domainoid score	I3726
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2967
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3015
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D534559at33208
OrthoFinder	1	1.000	-	-		FOG0003526
OrthoInspector	1	1.000	-	-		otm45673
orthoMCL	1	0.900	-	-		OOG6_102379
Panther	1	1.100	-	-	LDO	PTHR10696
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2892
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900