DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5321 and tmlhe

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_682831.3	Gene:	tmlhe / 555271	ZFINID:	ZDB-GENE-091204-144	Length:	410	Species:	Danio rerio

Alignment Length:	368	Identity:	108/368 - (29%)
Similarity:	171/368 - (46%)	Gaps:	33/368 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWL 113
            |..:||||:|....|::..:..|.||..:.|..|||...:.||.:  :.:.|.|.|.:|::|.||
Zfish    60 FDYVWLRDHCRSASCYNSKTNQRNLDTASIDLTIRPSKSRVDEHN--LFLTWPDGHVTRYNLAWL 122

  Fly   114 KERCFEPDKQQEYLRDFYRP----TTRHWSGAEFQDIAQHFSYDEVMSQDSVLMQWLQALAIYGV 174
            .:..:|..     :|...:|    ....:|.|:    ....::|:.||.|..|..:|....:||:
Zfish   123 AQNSYEGQ-----MRSAIQPRILWNAHIYSSAK----VPAANWDKFMSCDEELKNFLNNFLLYGI 178

  Fly   175 ALLRGAPLDEGVVRRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSV 239
            |.:.|.|........:..||..||.|.||..:...:.....:.||..|.|..|||..|::....:
Zfish   179 AFVEGVPPTLEATETVTQRVSLIRETIYGRMWNFTSDFSRGDTAYTKLALDRHTDTSYFQEPCGI 243

  Fly   240 NILHCVVQTDSPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHNIWRAPV 304
            .:.|| ::.:..||..:||||||.||.:.:..||:|:.||.:.:..:.:.:......|.|...||
Zfish   244 QVFHC-LRHEGTGGRTLLVDGFHAADTVLQQTPENFQLLSHVPIKHDYVENLSDHRNHMIGIGPV 307

  Fly   305 ICL---DEEG---RYTRINHSVPQRDSHFNVPLEEVLPWYESY-ALFVRLAIADSHAF-KTRPGD 361
            :.:   :.|.   ||...:.||..     .||.:.|..||.:: .|...|..||:..: |.:||.
Zfish   308 LNVYPWNNEVYMIRYNNYDRSVIN-----TVPHDVVRRWYVAHRKLTAELRRADNELWVKLKPGK 367

  Fly   362 VLTFNNIRLLHGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVL 404
            ||..:|.|:||||    :|....|.:.|.||..|.:.:..|.|
Zfish   368 VLFVDNWRVLHGR----ESFTGLRQLCGCYLTRDDVLNTARSL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	21/63 (33%)
		carnitine_bodg	49..405	CDD:274118	108/368 (29%)
		CAS_like	127..395	CDD:238154	81/279 (29%)
tmlhe	XP_682831.3	DUF971	49..122	CDD:294847	21/63 (33%)
		carnitine_TMLD	60..408	CDD:274119	108/368 (29%)
		CAS_like	132..397	CDD:238154	81/278 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D534559at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2023
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950