Protein Alignment CG5321 and TMLHE

DIOPT Version :10

• Sequence 1: NP_572967.2
• Gene: CG5321 / 32399
• FlyBaseID: FBgn0030575
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_060666.1
• Gene: TMLHE / 55217
• HGNCID: 18308
• Length: 421
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 112/373 - (30%)
• Similarity: 183/373 - (49%)
• Gaps: 39/373 - (10%)

  Fly    47 LTFPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLK 111
            :.|..:||||:|....|::..:..|.||..:.|..|:|.:::.||.:  :...|.|.|.:::.|.
Human    69 MRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDETT--LFFTWPDGHVTKYDLN 131

  Fly   112 WLKERCFEPDKQQEYLRDFYRPTTRHWSGAEFQDIAQHFSYD--EVMSQDSVLMQWLQALAIYGV 174
            ||.:..:|..||:     ..:|... |: ||....||..|.|  ..:..:..|.::||...:||:
Human   132 WLVKNSYEGQKQK-----VIQPRIL-WN-AEIYQQAQVPSVDCQSFLETNEGLKKFLQNFLLYGI 189

  Fly   175 ALLRGAPLDEGVVRRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSV 239
            |.:...|..:....:||:|:..||.|.||..:...:.....:.||..|.|..|||..|::....:
Human   190 AFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGI 254

  Fly   240 NILHCVVQTDSPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHN--IWRA 302
            .:.|| ::.:..||..:|||||:.|:.:.:..||:||.||::.:....|  ||..|.||  |...
Human   255 QVFHC-LKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYI--EDVGECHNHMIGIG 316

  Fly   303 PVICL---DEE---GRYTRINHSVPQRDSHFNVPLEEVLPWYESY-ALFVRLAIADSHAF-KTRP 359
            ||:.:   ::|   .||...:.:|..     .||.:.|..||.:: .|.:.|...::..: |.:|
Human   317 PVLNIYPWNKELYLIRYNNYDRAVIN-----TVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKP 376

  Fly   360 GDVLTFNNIRLLHGR---TGYDDSEESPRYIVGAYLDWDIIYSRLRVL 404
            |.||..:|.|:||||   |||       |.:.|.||..|.:.:..|:|
Human   377 GRVLFIDNWRVLHGRECFTGY-------RQLCGCYLTRDDVLNTARLL 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_572967.2	GBBH-like_N	<48..113	CDD:461840	19/64 (30%)
		CAS_like	127..395	CDD:238154	85/282 (30%)
TMLHE	NP_060666.1	carnitine_TMLD	70..419	CDD:274119	112/372 (30%)