DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5321 and Bbox1

DIOPT Version :9

Sequence 1:	NP_001285244.1	Gene:	CG5321 / 32399	FlyBaseID:	FBgn0030575	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_569719.1	Gene:	Bbox1 / 170442	MGIID:	1891372	Length:	387	Species:	Mus musculus

Alignment Length:	363	Identity:	141/363 - (38%)
Similarity:	209/363 - (57%)	Gaps:	9/363 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FPGIWLRDNCMCEDCFHGSSKSRKLDWDNFDTRIRPVSLQTDEQSKEVLVKWSDAHESRFSLKWL 113
            :|.:||||||.|.||:..|:|:|||..:..|..||...|..|.  |:|.:.|.:.|.|.|...||
Mouse    29 YPAVWLRDNCQCSDCYLHSAKARKLLLEALDVNIRIDDLTFDR--KKVYITWPNDHYSEFEANWL 91

  Fly   114 KERCFEPDKQQEYLRDFYRPTTRHWSGAEFQDIAQHFSYDEVMSQDSVLMQWLQALAIYGVALLR 178
            |:|||....:.....:.:.|..::| |:|.|  ....::::|::.|....:||.:|...|:..|.
Mouse    92 KKRCFSQQARARLQGELFLPECQYW-GSELQ--LPTLNFEDVLNDDDHAYKWLSSLKKVGIVRLT 153

  Fly   179 GAPLDEGVVRRLADRVGFIRRTTYGEEFVVQAKPGAQNFAYLSLTLPLHTDLPYYEYKPSVNILH 243
            ||....|.:.:|..|:||:..|.||..:.||.|..|.|.||.:..|..|||.|...:.|.|.:||
Mouse   154 GAADKRGEIIKLGKRIGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLH 218

  Fly   244 CVVQTDSPGGSNMLVDGFHVADLLRRDHPEDFERLSRIVVDWNDIGSEDGREFHNIWRAPVICLD 308
            |:.||.: ||.:.:||||:|...|:..:|:.|..||...||:.||| .|..:|....:..:|.||
Mouse   219 CIKQTVT-GGDSEIVDGFNVCQKLKEKNPQAFHILSSTFVDFTDIG-VDYCDFSVQSKHKIIELD 281

  Fly   309 EEGRYTRINHSVPQRDSHFNVPLEEVLPWYESYALFVRLAIAD--SHAFKTRPGDVLTFNNIRLL 371
            ::|:..|:|.:...||:.|:||:|.|.|:|.:...||.|..:.  .:.||..||||:||:|.|||
Mouse   282 DKGQVVRVNFNNATRDTVFDVPIERVQPFYAALKEFVDLMNSKEYKYTFKMNPGDVITFDNWRLL 346

  Fly   372 HGRTGYDDSEESPRYIVGAYLDWDIIYSRLRVLKKRLT 409
            |||..|:...|..|::.|||.|||::.||||:|::|:|
Mouse   347 HGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVT 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5321	NP_001285244.1	DUF971	<48..113	CDD:294847	26/63 (41%)
		carnitine_bodg	49..405	CDD:274118	138/357 (39%)
		CAS_like	127..395	CDD:238154	100/269 (37%)
Bbox1	NP_569719.1	CAS_like	16..381	CDD:381843	139/358 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843026
Domainoid	1	1.000	168	1.000	Domainoid score	I3814
eggNOG	1	0.900	-	-		E1_COG2175
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2967
Inparanoid	1	1.050	261	1.000	Inparanoid score	I3088
Isobase	1	0.950	-	0.909372	Normalized mean entropy	S3503
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003526
OrthoInspector	1	1.000	-	-		otm43601
orthoMCL	1	0.900	-	-		OOG6_102379
Panther	1	1.100	-	-	LDO	PTHR10696
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2023
SonicParanoid	1	1.000	-	-		X2892
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.730