Protein Alignment Tat and Gpt2

DIOPT Version :10

• Sequence 1: NP_572953.1
• Gene: Tat / 32381
• FlyBaseID: FBgn0030558
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_776291.1
• Gene: Gpt2 / 108682
• MGIID: 1915391
• Length: 522
• Species: Mus musculus
• Alignment Length: 546
• Identity: 117/546 - (21%)
• Similarity: 219/546 - (40%)
• Gaps: 103/546 - (18%)

  Fly    19 RASCTSRSPSEPESPAP-VTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIK 82
            ||:...|..|.|.:..| ...:.....:|.|.|:::.:  |..:|.:.|..:.:...|...:.::
Mouse     3 RAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPE--RSPRDRILTLESMNPQVKAVEYAVR 65

  Fly    83 G------SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGD-------PTTF----------GN 124
            |      .::.:.....|:        ||..|  :|..:|||       |.||          .|
Mouse    66 GPIVLKAGEIEMELQRGIK--------KPFTE--VIRANIGDAHAMGQQPITFLRQVMALCTYPN 120

  Fly   125 L-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDG-EIDANEVVLC 181
            |       :.|.:..:.:|.:........|:::||....|:.||.:..  |.|| ..|.:.:.|.
Mouse   121 LLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFIT--RRDGVPADPDNIYLT 183

  Fly   182 SGCSSALEYCILALADRG----QNVLVPRPGFCLYYTLAQGLD-IEVRYYDLLPDQQWRADLVQL 241
            :|.|..:...:..|...|    ..|::|.|.:.||..:...|| ::|.|| |..:..|..::.:|
Mouse   184 TGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAVQVNYY-LDEENCWALNVDEL 247

  Fly   242 ESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVF-PGSKH 300
            ...:.:     :...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|: |..:.
Mouse   248 RRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRF 312

  Fly   301 LAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--MCGR 354
            .:...:        ::.|.:.|....:|.::.. |:|.|::.|.:....::..:|.|.:  :|..
Mouse   313 HSFKKVLYQMGHEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPP 377

  Fly   355 ILGSNTIIQGALPDILTKTPQSYFDG----------VIDVLHSNAMLAYKMLKQVRGLDPVMPNG 409
            :.|     |.|: ||:...|:...:.          |:..|...|.|...:..||.|:......|
Mouse   378 VSG-----QAAM-DIVVNPPEPGEESFEQFSREKEFVLGNLAKKAKLTEDLFNQVPGIQCNPLQG 436

  Fly   410 AMY-----MMIGVSIERFPEFK--DDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTVPGA 464
            |||     ::...::|.....|  .|..:..:::.|..:..:|||.|   |...:.|:.:..|..
Mouse   437 AMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVD 501

  Fly   465 MIEEACSRIAEFCDRHYKKESRNFIE 490
            .::....::.:|   |.|     |:|
Mouse   502 KLKTVLHKVKDF---HLK-----FLE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tat	NP_572953.1	tyr_amTase_E	79..481	CDD:273529	100/474 (21%)
Gpt2	NP_776291.1	PTZ00377	48..522	CDD:240391	106/499 (21%)