Protein Alignment Dus2 and Dus2

DIOPT Version :10

• Sequence 1: NP_572950.2
• Gene: Dus2 / 32377
• FlyBaseID: FBgn0030554
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_079794.1
• Gene: Dus2 / 66369
• MGIID: 1913619
• Length: 493
• Species: Mus musculus
• Alignment Length: 457
• Identity: 226/457 - (49%)
• Similarity: 301/457 - (65%)
• Gaps: 21/457 - (4%)

  Fly    20 LDYRNKLILAPMVRVGTLPMRLLALEMGADIVYTEELVDIKLIKSIRRPNPALGTVDFVDPSDGT 84
            |.|.|||||||||||||||||||||:.||||||.|||:|:|:::..|..|..|.|||||.|.| .
Mouse     8 LCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMLQCKRVVNEVLSTVDFVAPDD-R 71

  Fly    85 IVFRTCAQETSRLVLQMGTSDAGRALAVGKLLQRDISGLDINMGCPKEFSIKGGMGAALLADPDK 149
            :|||||.:|.||:|.|||||||.|||||.:|::.|::|:|:|||||||:|.|||||||||:||||
Mouse    72 VVFRTCEREQSRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDK 136

  Fly   150 AAHILRTLCSGLDIPVTCKIRILPDVEGTIDLVQKLAATGIAAIGIHARTRDERPQHPAHPEVLR 214
            ...||.||..|...||||||||||.:|.|::||:::..|||:||.:|.|.||||||||...||:|
Mouse   137 IEKILSTLVKGTHRPVTCKIRILPSLEDTLNLVKRIERTGISAIAVHGRNRDERPQHPVSCEVIR 201

  Fly   215 AVAQAVDIPIIANGGS-KNMHCYDDLRKFQMECGADSVMVARAAQINVSIFRPEGLLPMDELIEK 278
            |:|:.:.||:|||||| .::..:.|:..|:....|.||||||||..|.|||..:||.|::|:::|
Mouse   202 AIAETLSIPVIANGGSHDHIQQHVDIEDFRQATAASSVMVARAAMWNPSIFLKDGLRPLEEVMQK 266

  Fly   279 YLRLCVDYDNAPHNAKYCVQSILRELQETPRGKRFLQCQTLQQICEIWELGDYCRRKQRELKTMG 343
            |:|..|.|||...|.|||:..:|||..|:|:|:.....|:.|:|||.:.||.:.....|||
Mouse   267 YIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETIREL---- 327

  Fly   344 NSGRAEV--EPPEALAKRQKLEDAAIAITDEYDGIICRHMPFLRSTYPSDNHLPKTQLYVHAVKT 406
            ::.||::  :.|||      :|:.|    ::..|||...:.|.|..|| ....||..|.....:.
Mouse   328 DARRADLLAKTPEA------VEEPA----EDTSGIIKMAIRFDRRAYP-PQITPKMCLLEWCRRE 381

  Fly   407 GKSPPAYETQQ--CDKLFRSICTYDGQRFSSSFWEKNKKQAEQGAALVALLHLGQLEAEVLRDNG 469
            ....|.|||.|  .|::|.|:.|...|::.|:.|:|:||.|||.||:|.|...|..|..:..::.
Mouse   382 KLPQPVYETVQRTIDRMFCSVVTVAEQKYQSTLWDKSKKLAEQTAAIVCLRSQGLPEGRLGEESP 446

  Fly   470 SL 471
            ||
Mouse   447 SL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dus2	NP_572950.2	DUS_like_FMN	25..266	CDD:239200	149/241 (62%)
		DSRM_DUS2L	394..458	CDD:380700	25/65 (38%)
Dus2	NP_079794.1	Catalytic domain. /evidence=ECO:0000250|UniProtKB:Q9NX74	1..333		183/325 (56%)
		DUS_like_FMN	13..252	CDD:239200	147/239 (62%)
		Interaction with tRNA. /evidence=ECO:0000250|UniProtKB:Q9NX74	367..371		0/3 (0%)
		DSRM_DUS2L	369..436	CDD:380700	24/68 (35%)
		Interaction with tRNA. /evidence=ECO:0000250|UniProtKB:Q9NX74	420..424		0/3 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	438..472		7/22 (32%)