Protein Alignment Clic and clic4

DIOPT Version :10

• Sequence 1: NP_572928.1
• Gene: Clic / 32349
• FlyBaseID: FBgn0030529
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001007908.1
• Gene: clic4 / 493290
• XenbaseID: XB-GENE-958154
• Length: 252
• Species: Xenopus tropicalis
• Alignment Length: 227
• Identity: 74/227 - (32%)
• Similarity: 113/227 - (49%)
• Gaps: 27/227 - (11%)

  Fly    23 IELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPPIL 87
            :||.:||.: ||...|.|.|.|..||.|:    ||.:...|||||:::.|.|.:.....||||.:
 Frog    18 VELFVKAGS-DGESIGNCPFSQRLFMILW----LKGVVFNVTTVDLKRKPADLQNLAPGTHPPFI 77

  Fly    88 IDNGLAILENEKIERHIMKNI-PGGY-NLFVQDKEVATLIENLYVK----LKLMLVKKDEAKNNA 146
            ..|.....:..|||..:.:.: |..| .|..:..|..|...:::.|    :|......:||....
 Frog    78 TYNHEVKTDVNKIEEFLEEVLCPPKYRKLAAKHPESNTAGMDIFAKFSAYIKNSRPDNNEALERG 142

  Fly   147 LLSHLRKINDHLSA----------------RNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDF 195
            ||..|:|::|:|::                .|.:||.|:.|...||.|:|:|..|:|..|.:..|
 Frog   143 LLKTLQKLDDYLNSPLPDEIDENSMDDITQSNRKFLDGEEMTLADCNLLPKLHIIKVVTKKYRGF 207

  Fly   196 EIPTHLTALWRYMYHMYQLDAFTQSCPADQDI 227
            |||..:|.:|||:.:.|..|.||.:||.|::|
 Frog   208 EIPKSMTGIWRYLSNAYSKDEFTNTCPGDREI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clic	NP_572928.1	GST_N_CLIC	18..112	CDD:239359	31/89 (35%)
		GST_C_CLIC	118..232	CDD:198307	41/130 (32%)
clic4	NP_001007908.1	O-ClC	17..250	CDD:129941	74/227 (33%)