Protein Alignment inaE and dagl-2

DIOPT Version :10

• Sequence 1: NP_001138195.1
• Gene: inaE / 32343
• FlyBaseID: FBgn0261244
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: NP_741085.1
• Gene: dagl-2 / 3565075
• WormBaseID: WBGene00018364
• Length: 683
• Species: Caenorhabditis elegans
• Alignment Length: 779
• Identity: 202/779 - (25%)
• Similarity: 350/779 - (44%)
• Gaps: 182/779 - (23%)

  Fly     1 MPGLVVFRRRWSVGSDDLVVP--GAFLLTIHFICFVIVSVSLVIFEY----NTRILSVKLLFYHL 59
            ||.||.|.|:|::||||.|.|  ...|:.:.::.|   .||:.:|.:    :|..|:::||
 Worm     1 MPSLVAFNRQWNIGSDDFVFPEITEALVRLSWVAF---GVSVFVFHFPLACSTHNLTLQLL---- 58

  Fly    60 IGYLLILFFSICVEIGICVISMRGSILDAEARTSINIWIYLKSLVILFDIAWLAVGSVWLGHYYT 124
             |.|:|...:|.:.|...|||.||:|::::.|..|...:|::..:.:.:||...:.::   |.:.
 Worm    59 -GLLVINVITILLAILTAVISARGTIMNSQPRKLIPRLLYIRLPIFIAEIALTILATI---HAFK 119

  Fly   125 TAPIDDPKKVYIAIIICNWALVV-ITLITIWCTFDAAGRSWVKMKKYQRSMRETESRFNYKRSNS 188
            :....:.         |::|.:. :|:|..|.....|....|.:  :..:..|.|.     .::.
 Worm   120 STNGGEG---------CDFATIARVTIILEWFLIFTAFAGLVIV--FHLTENELED-----SASI 168

  Fly   189 MNRNWRQRKVMRAYQDSWDHRCRLLFCCMGSSERNRNSFTDIARLLSDFFRELDVVPSDVVAGLV 253
            ..::|.:|  ||.::...||..|:             :..|:|.|:|.||.:.|:|||||||||:
 Worm   169 AQKSWSRR--MRIFKIGQDHSMRV-------------ALDDLAILISSFFVDSDLVPSDVVAGLL 218

  Fly   254 LLRKFQRLEREAIVRQRKNGTYEFLSGVPITER-----TQFLALNDAKNYDFFQTVIHYMYFAQG 313
            |            .....|..|.     |:.::     .:::.|.||:         ::::.|..
 Worm   219 L------------AYHSPNNQYP-----PVKDKEHESVPKWMNLKDAE---------YFLHHATC 257

  Fly   314 AYGWPMYVIIN--RSKMWHLVPELKCFG-CCCGTS------------DDTE-------------V 350
            .||||.|::.|  ...::.|..:|:|.| ..|..|            :.||             |
 Worm   258 VYGWPTYILYNCGLKSIYRLFRKLQCCGRMRCAQSPCVVQQQRRERIELTELSNGKLVKKGKSMV 322

  Fly   351 IQDNCCLCNYAALKKTLQLGDIDIVYATYHVDVGETPFFVAIDYTHRAVVISIRGTLSMKDILTD 415
            ::||||.||.||:....:..:||:.:.::...|.|.||.|..|:..:::||:|||:.|:.|::||
 Worm   323 VEDNCCYCNTAAVVLANEARNIDLQFMSFRNRVYEVPFAVIADHDKKSIVITIRGSCSLIDLVTD 387

  Fly   416 LNAEGEVLPLQPPRD-------------DWLGHKGMVQAAIYIRNKLQEENLIERALQRNPDRQT 467
            |:.|.|::.:...:|             |...|:||:::|.|:.:.|.:..::......||
 Worm   388 LSLEDELMTVDVDQDATLREDEEIDKRGDVRVHRGMLRSARYVFDTLNKNKILNDLFISNP---- 448

  Fly   468 HTFDLVLVGHSLGAGTAAILAILLKPEHPTLQCFSYSPPGGLLSMPAVEYSKSFITSVVLGKDVV 532
             ::.||:.|||||||..::|.:|||.|:|::.|::::|||.::|....:..:.::.|||.|.|:|
 Worm   449 -SYQLVVCGHSLGAGVGSLLTMLLKQEYPSVICYAFAPPGCVISEFGQDEMEKYVMSVVSGDDIV 512

  Fly   533 PRIGLNQMEALRADLIN---AIQRS-------------VDPKWKTISCSVICCGCGPE-PTSVVN 580
            .|:....:..||..:..   |.||:             ....|......|......|: ||:...
 Worm   513 SRMSFQSLHRLRERVFQELLACQRAKYEILIRGVYQLFFKYPWGDELSGVPRISASPDSPTTPDI 577

  Fly   581 MSGQDTHINQYQEERGTARSTS-AHPTDSSIALTLHQP-------LYPPGRIIHIVRHHPKPDEQ 637
            .|...|..|.|    |.:..|| |.||...     ..|       ||.|||:|::     ..|:
 Worm   578 ESALLTRRNSY----GASDPTSEASPTPPQ-----RNPNHNKRLQLYVPGRVIYL-----SADQ- 627

  Fly   638 KYDSGWRNVLKNREPVYQAIWADSTDFDEVLISPVMLQDHMPDKVLAALKKVVTTSGPRKPQRQ 701
              |:|          .....|.|.....:|.:|..:|.||:|    ||::|.:.::.....||:
 Worm   628 --DTG----------ATVETWIDPKCLSDVKLSVSVLSDHLP----AAVQKFLNSAAITFEQRE 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaE	NP_001138195.1	Lipase_3	300..542	CDD:238287	81/282 (29%)
dagl-2	NP_741085.1	Lipase_3	328..522	CDD:238287	62/198 (31%)